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MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells.

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Title: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells.
Authors: Lai X; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK., Broderick R; Division of Cancer Biology, Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK., Bergoglio V; Cancer Research Center of Toulouse, Université de Toulouse, Inserm, CNRS, UPS, Equipe labellisée Ligue Contre le Cancer, Laboratoire d'excellence Toulouse Cancer, 2 Avenue Hubert Curien, Toulouse 31037, France., Zimmer J; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK., Badie S; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK., Niedzwiedz W; Division of Cancer Biology, Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK., Hoffmann JS; Cancer Research Center of Toulouse, Université de Toulouse, Inserm, CNRS, UPS, Equipe labellisée Ligue Contre le Cancer, Laboratoire d'excellence Toulouse Cancer, 2 Avenue Hubert Curien, Toulouse 31037, France., Tarsounas M; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.
Source: Nature communications [Nat Commun] 2017 Jul 17; Vol. 8, pp. 15983. Date of Electronic Publication: 2017 Jul 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells.
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  Data: <searchLink fieldCode="AU" term="%22Lai+X%22">Lai X</searchLink>; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Broderick+R%22">Broderick R</searchLink>; Division of Cancer Biology, Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK.<br /><searchLink fieldCode="AU" term="%22Bergoglio+V%22">Bergoglio V</searchLink>; Cancer Research Center of Toulouse, Université de Toulouse, Inserm, CNRS, UPS, Equipe labellisée Ligue Contre le Cancer, Laboratoire d'excellence Toulouse Cancer, 2 Avenue Hubert Curien, Toulouse 31037, France.<br /><searchLink fieldCode="AU" term="%22Zimmer+J%22">Zimmer J</searchLink>; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Badie+S%22">Badie S</searchLink>; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Niedzwiedz+W%22">Niedzwiedz W</searchLink>; Division of Cancer Biology, Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK.<br /><searchLink fieldCode="AU" term="%22Hoffmann+JS%22">Hoffmann JS</searchLink>; Cancer Research Center of Toulouse, Université de Toulouse, Inserm, CNRS, UPS, Equipe labellisée Ligue Contre le Cancer, Laboratoire d'excellence Toulouse Cancer, 2 Avenue Hubert Curien, Toulouse 31037, France.<br /><searchLink fieldCode="AU" term="%22Tarsounas+M%22">Tarsounas M</searchLink>; Genome Stability and Tumourigenesis Group, Department of Oncology, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2017 Jul 17; Vol. 8, pp. 15983. <i>Date of Electronic Publication: </i>2017 Jul 17.
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