Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia.
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| Title: | Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. |
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| Authors: | Leonenko G; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Richards AL; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Walters JT; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Pocklington A; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Chambert K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Al Eissa MM; Division of Psychiatry, Molecular Psychiatry Laboratory, University College London, London, UK., Sharp SI; Division of Psychiatry, Molecular Psychiatry Laboratory, University College London, London, UK., O'Brien NL; Division of Psychiatry, Molecular Psychiatry Laboratory, University College London, London, UK., Curtis D; UCL Genetics Institute, UCL, London, UK., Bass NJ; Division of Psychiatry, Molecular Psychiatry Laboratory, University College London, London, UK., McQuillin A; Division of Psychiatry, Molecular Psychiatry Laboratory, University College London, London, UK., Hultman C; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden., Moran JL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts., McCarroll SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Genetics, Harvard Medical School, Boston, Massachusetts., Sklar P; Icahn School of Medicine at Mount Sinai, New York, New York., Neale BM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Holmans PA; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Owen MJ; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.; Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, North Carolina., O'Donovan MC; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK. |
| Source: | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [Am J Med Genet B Neuropsychiatr Genet] 2017 Oct; Vol. 174 (7), pp. 724-731. Date of Electronic Publication: 2017 Jul 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-485X (Electronic) Linking ISSN: 15524841 NLM ISO Abbreviation: Am J Med Genet B Neuropsychiatr Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-485X |
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| DOI: | 10.1002/ajmg.b.32560 |
