View in EDS HTML Full Text PDF Full Text

Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.

Saved in:
Bibliographic Details
Title: Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Authors: Ruhrmann S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Ewing E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Piket E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Kular L; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Cetrulo Lorenzi JC; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Department of Genetics, Medical School of Ribeirão Preto, São Paulo University, Ribeirão Preto, Brazil., Fernandes SJ; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden., Morikawa H; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden., Aeinehband S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Sayols-Baixeras S; Cardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain/ Universitat Pompeu Fabra (UPF), Barcelona, Spain., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Absher DM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA., Tegner J; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden/ Biological and Environmental Sciences and Engineering Division, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia., Gomez-Cabrero D; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Mucosal & Salivary Biology Division, Dental Institute, King's College London, London, UK., Piehl F; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Source: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2018 Sep; Vol. 24 (10), pp. 1288-1300. Date of Electronic Publication: 2017 Aug 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 28766461
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ruhrmann+S%22">Ruhrmann S</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ewing+E%22">Ewing E</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Piket+E%22">Piket E</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kular+L%22">Kular L</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Cetrulo+Lorenzi+JC%22">Cetrulo Lorenzi JC</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Department of Genetics, Medical School of Ribeirão Preto, São Paulo University, Ribeirão Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Fernandes+SJ%22">Fernandes SJ</searchLink>; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Morikawa+H%22">Morikawa H</searchLink>; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Aeinehband+S%22">Aeinehband S</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Sayols-Baixeras+S%22">Sayols-Baixeras S</searchLink>; Cardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain/ Universitat Pompeu Fabra (UPF), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Aslibekyan+S%22">Aslibekyan S</searchLink>; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Absher+DM%22">Absher DM</searchLink>; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.<br /><searchLink fieldCode="AU" term="%22Arnett+DK%22">Arnett DK</searchLink>; College of Public Health, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Tegner+J%22">Tegner J</searchLink>; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden/ Biological and Environmental Sciences and Engineering Division, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Gomez-Cabrero+D%22">Gomez-Cabrero D</searchLink>; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Mucosal & Salivary Biology Division, Dental Institute, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Piehl+F%22">Piehl F</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Jagodic+M%22">Jagodic M</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229509185%22">Multiple sclerosis (Houndmills, Basingstoke, England)</searchLink> [Mult Scler] 2018 Sep; Vol. 24 (10), pp. 1288-1300. <i>Date of Electronic Publication: </i>2017 Aug 02.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9509185 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-0970 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213524585%22">13524585 </searchLink><i>NLM ISO Abbreviation: </i>Mult Scler <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=28766461
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1177/1352458517721356
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1288
    Titles:
      – TitleFull: Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ruhrmann S
      – PersonEntity:
          Name:
            NameFull: Ewing E
      – PersonEntity:
          Name:
            NameFull: Piket E
      – PersonEntity:
          Name:
            NameFull: Kular L
      – PersonEntity:
          Name:
            NameFull: Cetrulo Lorenzi JC
      – PersonEntity:
          Name:
            NameFull: Fernandes SJ
      – PersonEntity:
          Name:
            NameFull: Morikawa H
      – PersonEntity:
          Name:
            NameFull: Aeinehband S
      – PersonEntity:
          Name:
            NameFull: Sayols-Baixeras S
      – PersonEntity:
          Name:
            NameFull: Aslibekyan S
      – PersonEntity:
          Name:
            NameFull: Absher DM
      – PersonEntity:
          Name:
            NameFull: Arnett DK
      – PersonEntity:
          Name:
            NameFull: Tegner J
      – PersonEntity:
          Name:
            NameFull: Gomez-Cabrero D
      – PersonEntity:
          Name:
            NameFull: Piehl F
      – PersonEntity:
          Name:
            NameFull: Jagodic M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2018 Sep
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 1477-0970
          Numbering:
            – Type: volume
              Value: 24
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Multiple sclerosis (Houndmills, Basingstoke, England)
              Type: main
ResultId 1