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Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.

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Title: Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.
Authors: Alhadj Ali M; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Liu YF; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK.; Department of Diabetes and Endocrinology, Guy's and St Thomas' Hospital National Health Service (NHS) Foundation Trust, London SE19RT, UK., Arif S; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Tatovic D; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Shariff H; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Gibson VB; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Yusuf N; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Baptista R; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK.; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London SE19RT, UK., Eichmann M; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Petrov N; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London SE19RT, UK., Heck S; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London SE19RT, UK., Yang JHM; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Tree TIM; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Pujol-Autonell I; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Yeo L; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Baumard L; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK., Stenson R; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Howell A; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Clark A; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Boult Z; Clinical Research Facility, University Hospital of Wales, Cardiff CF14 4XN, UK., Powrie J; Department of Diabetes and Endocrinology, Guy's and St Thomas' Hospital National Health Service (NHS) Foundation Trust, London SE19RT, UK., Adams L; Department of Diabetes and Endocrinology, Guy's and St Thomas' Hospital National Health Service (NHS) Foundation Trust, London SE19RT, UK., Wong FS; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Luzio S; Diabetes Research Unit Cymru, Swansea University, Swansea SA2 8PP, UK., Dunseath G; Diabetes Research Unit Cymru, Swansea University, Swansea SA2 8PP, UK., Green K; Joint Clinical Research Unit, University Hospitals Bristol Foundation Trust, Bristol BS2 8HW, UK., O'Keefe A; Joint Clinical Research Unit, University Hospitals Bristol Foundation Trust, Bristol BS2 8HW, UK., Bayly G; Joint Clinical Research Unit, University Hospitals Bristol Foundation Trust, Bristol BS2 8HW, UK., Thorogood N; Joint Clinical Research Unit, University Hospitals Bristol Foundation Trust, Bristol BS2 8HW, UK., Andrews R; Joint Clinical Research Unit, University Hospitals Bristol Foundation Trust, Bristol BS2 8HW, UK., Leech N; Diabetes and Endocrinology Department, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle NE1 4LP, UK., Joseph F; Diabetes and Endocrinology Department, Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL, UK., Nair S; Diabetes and Endocrinology Department, Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL, UK., Seal S; Diabetes and Endocrinology Department, Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL, UK., Cheung H; Diabetes and Endocrinology Department, Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL, UK., Beam C; Division of Epidemiology and Biostatistics, Western Michigan University School of Medicine, MI 49008, USA., Hills R; Haematology Clinical Trials Unit, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Peakman M; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London SE19RT, UK. mark.peakman@kcl.ac.uk.; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London SE19RT, UK.; King's Health Partners Institute of Diabetes, Endocrinology and Obesity, London SE19RT, UK., Dayan CM; Diabetes Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Source: Science translational medicine [Sci Transl Med] 2017 Aug 09; Vol. 9 (402).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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