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REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial.

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Title: REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial.
Authors: Macdonald SPJ; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia. stephen.macdonald@uwa.edu.au.; Emergency Department, Royal Perth Hospital, Perth, WA, Australia. stephen.macdonald@uwa.edu.au.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia. stephen.macdonald@uwa.edu.au., Taylor DM; Emergency Department, Austin Hospital, Melbourne, VIC, Australia.; Department of Medicine, University of Melbourne, Melbourne, VIC, Australia., Keijzers G; Emergency Department, Gold Coast University Hospital, Gold Coast, QLD, Australia.; School of Medicine, Bond University, Gold Coast, QLD, Australia.; School of Medical Sciences, Griffith University, Gold Coast, QLD, Australia., Arendts G; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Fiona Stanley Hospital, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia., Fatovich DM; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Royal Perth Hospital, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia., Kinnear FB; Emergency and Children's Services, The Prince Charles Hospital, Brisbane, QLD, Australia., Brown SGA; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Royal Hobart Hospital, Hobart, TAS, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia., Bellomo R; Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia.; School of Medicine, University of Melbourne, Melbourne, VIC, Australia., Burrows S; School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia., Fraser JF; School of Medicine, Bond University, Gold Coast, QLD, Australia.; Critical Care Research Group, The Prince Charles Hospital, Brisbane, QLD, Australia.; School of Medicine, University of Queensland, Brisbane, QLD, Australia., Litton E; Department of Intensive Care, Fiona Stanley Hospital, Perth, WA, Australia., Ascencio-Lane JC; Emergency Department, Royal Hobart Hospital, Hobart, TAS, Australia., Anstey M; Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, WA, Australia., McCutcheon D; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.; Emergency Department, Armadale Health Service, Perth, WA, Australia., Smart L; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia., Vlad I; Emergency Department, Sir Charles Gairdner Hospital, Perth, WA, Australia., Winearls J; School of Medical Sciences, Griffith University, Gold Coast, QLD, Australia.; School of Medicine, University of Queensland, Brisbane, QLD, Australia.; Department of Intensive Care, Gold Coast University Hospital, Gold Coast, QLD, Australia., Wibrow B; Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, WA, Australia.
Source: Trials [Trials] 2017 Aug 29; Vol. 18 (1), pp. 399. Date of Electronic Publication: 2017 Aug 29.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Pragmatic Clinical Trial
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
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  Data: REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Macdonald+SPJ%22">Macdonald SPJ</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia. stephen.macdonald@uwa.edu.au.; Emergency Department, Royal Perth Hospital, Perth, WA, Australia. stephen.macdonald@uwa.edu.au.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia. stephen.macdonald@uwa.edu.au.<br /><searchLink fieldCode="AU" term="%22Taylor+DM%22">Taylor DM</searchLink>; Emergency Department, Austin Hospital, Melbourne, VIC, Australia.; Department of Medicine, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Keijzers+G%22">Keijzers G</searchLink>; Emergency Department, Gold Coast University Hospital, Gold Coast, QLD, Australia.; School of Medicine, Bond University, Gold Coast, QLD, Australia.; School of Medical Sciences, Griffith University, Gold Coast, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Arendts+G%22">Arendts G</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Fiona Stanley Hospital, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Fatovich+DM%22">Fatovich DM</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Royal Perth Hospital, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Kinnear+FB%22">Kinnear FB</searchLink>; Emergency and Children's Services, The Prince Charles Hospital, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+SGA%22">Brown SGA</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Emergency Department, Royal Hobart Hospital, Hobart, TAS, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Bellomo+R%22">Bellomo R</searchLink>; Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia.; School of Medicine, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Burrows+S%22">Burrows S</searchLink>; School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Fraser+JF%22">Fraser JF</searchLink>; School of Medicine, Bond University, Gold Coast, QLD, Australia.; Critical Care Research Group, The Prince Charles Hospital, Brisbane, QLD, Australia.; School of Medicine, University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Litton+E%22">Litton E</searchLink>; Department of Intensive Care, Fiona Stanley Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Ascencio-Lane+JC%22">Ascencio-Lane JC</searchLink>; Emergency Department, Royal Hobart Hospital, Hobart, TAS, Australia.<br /><searchLink fieldCode="AU" term="%22Anstey+M%22">Anstey M</searchLink>; Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22McCutcheon+D%22">McCutcheon D</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.; Emergency Department, Armadale Health Service, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Smart+L%22">Smart L</searchLink>; Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, WA, Australia.; Division of Emergency Medicine, Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Vlad+I%22">Vlad I</searchLink>; Emergency Department, Sir Charles Gairdner Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Winearls+J%22">Winearls J</searchLink>; School of Medical Sciences, Griffith University, Gold Coast, QLD, Australia.; School of Medicine, University of Queensland, Brisbane, QLD, Australia.; Department of Intensive Care, Gold Coast University Hospital, Gold Coast, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Wibrow+B%22">Wibrow B</searchLink>; Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, WA, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2017 Aug 29; Vol. 18 (1), pp. 399. <i>Date of Electronic Publication: </i>2017 Aug 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE
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