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High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing.

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Title: High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing.
Authors: Guan Y; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Mayba O; Department of Bioinformatics, Genentech, Inc., South San Francisco, California., Sandmann T; Department of Bioinformatics, Genentech, Inc., South San Francisco, California., Lu S; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Choi Y; Department of Biostatistics, Genentech, Inc., South San Francisco, California., Darbonne WC; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Leveque V; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Ryner L; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Humke E; Department of Clinical Science, Genentech, Inc., South San Francisco, California., Tam NWR; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Sujathasarma S; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Cheung A; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Bourgon R; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Lackner MR; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California., Wang Y; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California. Electronic address: wang.yulei@gene.com.
Source: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2017 Nov; Vol. 19 (6), pp. 921-932. Date of Electronic Publication: 2017 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing.
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  Data: <searchLink fieldCode="AU" term="%22Guan+Y%22">Guan Y</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Mayba+O%22">Mayba O</searchLink>; Department of Bioinformatics, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Sandmann+T%22">Sandmann T</searchLink>; Department of Bioinformatics, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Lu+S%22">Lu S</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Choi+Y%22">Choi Y</searchLink>; Department of Biostatistics, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Darbonne+WC%22">Darbonne WC</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Leveque+V%22">Leveque V</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Ryner+L%22">Ryner L</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Humke+E%22">Humke E</searchLink>; Department of Clinical Science, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Tam+NWR%22">Tam NWR</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Sujathasarma+S%22">Sujathasarma S</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Cheung+A%22">Cheung A</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Bourgon+R%22">Bourgon R</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Lackner+MR%22">Lackner MR</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California. Electronic address: wang.yulei@gene.com.
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  Data: <searchLink fieldCode="JN" term="%22100893612%22">The Journal of molecular diagnostics : JMD</searchLink> [J Mol Diagn] 2017 Nov; Vol. 19 (6), pp. 921-932. <i>Date of Electronic Publication: </i>2017 Sep 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100893612 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1943-7811 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215251578%22">15251578 </searchLink><i>NLM ISO Abbreviation: </i>J Mol Diagn <i>Subsets: </i>MEDLINE
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              Text: 2017 Nov
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