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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

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Title: Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.
Authors: Infante JR; Early Development Oncology, Janssen Research & Development, LLC, Welsh & McKean Roads, Spring House, PA 19477, USA., Korn RL; Scottsdale Medical Imaging, 9700 N. 91st Suite C-200, Scottsdale, AZ 85258, USA., Rosen LS; Division of Hematology-Oncology, University of California - Los Angeles, 2020 Santa Monica Boulevard, Suite 600, Santa Monica, CA 90404, USA., LoRusso P; Yale Cancer Center, PO Box 208028, New Haven, CT 06520, USA., Dychter SS; Fate Therapeutics, Inc., 3535 General Atomics Court, San Diego, CA 92121, USA., Zhu J; SBIO Pte, Ltd., 1 Science Park Road, #05-09, The Capricorn Science Park 2, Singapore, 117 528, Singapore., Maneval DC; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA., Jiang P; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA., Shepard HM; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA., Frost G; F1 Bioventures LLC, 505 S. Flagler Drive, West Palm Beach, FL 33401, USA., Von Hoff DD; Translational Genomics Research Institute (TGen), 445 N. Fifth Street, Phoenix, AZ 85004, USA., Borad MJ; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA., Ramanathan RK; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA.
Source: British journal of cancer [Br J Cancer] 2018 Jan; Vol. 118 (2), pp. 153-161. Date of Electronic Publication: 2017 Sep 26.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.
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  Data: <searchLink fieldCode="AU" term="%22Infante+JR%22">Infante JR</searchLink>; Early Development Oncology, Janssen Research & Development, LLC, Welsh & McKean Roads, Spring House, PA 19477, USA.<br /><searchLink fieldCode="AU" term="%22Korn+RL%22">Korn RL</searchLink>; Scottsdale Medical Imaging, 9700 N. 91st Suite C-200, Scottsdale, AZ 85258, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+LS%22">Rosen LS</searchLink>; Division of Hematology-Oncology, University of California - Los Angeles, 2020 Santa Monica Boulevard, Suite 600, Santa Monica, CA 90404, USA.<br /><searchLink fieldCode="AU" term="%22LoRusso+P%22">LoRusso P</searchLink>; Yale Cancer Center, PO Box 208028, New Haven, CT 06520, USA.<br /><searchLink fieldCode="AU" term="%22Dychter+SS%22">Dychter SS</searchLink>; Fate Therapeutics, Inc., 3535 General Atomics Court, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; SBIO Pte, Ltd., 1 Science Park Road, #05-09, The Capricorn Science Park 2, Singapore, 117 528, Singapore.<br /><searchLink fieldCode="AU" term="%22Maneval+DC%22">Maneval DC</searchLink>; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+P%22">Jiang P</searchLink>; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Shepard+HM%22">Shepard HM</searchLink>; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Frost+G%22">Frost G</searchLink>; F1 Bioventures LLC, 505 S. Flagler Drive, West Palm Beach, FL 33401, USA.<br /><searchLink fieldCode="AU" term="%22Von+Hoff+DD%22">Von Hoff DD</searchLink>; Translational Genomics Research Institute (TGen), 445 N. Fifth Street, Phoenix, AZ 85004, USA.<br /><searchLink fieldCode="AU" term="%22Borad+MJ%22">Borad MJ</searchLink>; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA.<br /><searchLink fieldCode="AU" term="%22Ramanathan+RK%22">Ramanathan RK</searchLink>; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2018 Jan; Vol. 118 (2), pp. 153-161. <i>Date of Electronic Publication: </i>2017 Sep 26.
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  Data: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
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