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Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications.

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Title: Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications.
Authors: Hageman GS; a Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa.; b Center for the Study of Macular Degeneration, University of California, Santa Barbara, CA., Hancox LS; a Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa., Taiber AJ; a Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa., Gehrs KM; a Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa., Anderson DH; b Center for the Study of Macular Degeneration, University of California, Santa Barbara, CA.; c Neuroscience Research Institute, University of California, Santa Barbara, CA., Johnson LV; b Center for the Study of Macular Degeneration, University of California, Santa Barbara, CA.; c Neuroscience Research Institute, University of California, Santa Barbara, CA., Radeke MJ; b Center for the Study of Macular Degeneration, University of California, Santa Barbara, CA.; c Neuroscience Research Institute, University of California, Santa Barbara, CA., Kavanagh D; d Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St Louis, MO., Richards A; d Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St Louis, MO., Atkinson J; d Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St Louis, MO., Meri S; e Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland., Bergeron J; f SAIC-Frederick, NCI-Frederick, Frederick, Maryland., Zernant J; h Department of Ophthalmology, Columbia University, New York., Merriam J; h Department of Ophthalmology, Columbia University, New York., Gold B; g Laboratory of Genomic Diversity, National Cancer Institute, NCI-Frederick, Frederick, Maryland., Allikmets R; h Department of Ophthalmology, Columbia University, New York.; i Department of Pathology and Cell Biology, Columbia University, New York., Dean M; g Laboratory of Genomic Diversity, National Cancer Institute, NCI-Frederick, Frederick, Maryland.
Source: Annals of medicine [Ann Med] 2006; Vol. 38 (8), pp. 592-604.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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