Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2's-hydroxy-3's-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors.
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| Title: | Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2's-hydroxy-3's-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors. |
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| Authors: | Kandalkar SR; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India; Department of Organic Chemistry, Andhra university, Visakhapatnam 530003, India., Ramaiah PA; Department of Organic Chemistry, Andhra university, Visakhapatnam 530003, India., Joshi M; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Wavhal A; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Waman Y; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Raje AA; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Tambe A; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Ansari S; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., De S; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Palle VP; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Mookhtiar KA; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India., Deshpande AM; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India. Electronic address: anil.deshpande@advinus.com., Barawkar DA; Advinus Therapeutics Ltd., Drug Discovery Facility, Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi Infotech Park, Hinjewadi, Pune 411 057, India. Electronic address: dinesh.b@advinus.com. |
| Source: | Bioorganic & medicinal chemistry [Bioorg Med Chem] 2017 Oct 15; Vol. 25 (20), pp. 5799-5819. Date of Electronic Publication: 2017 Sep 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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