Investigation of Deteriorated Dissolution of Amorphous Itraconazole: Description of Incompatibility with Magnesium Stearate and Possible Solutions.

Saved in:
Bibliographic Details
Title: Investigation of Deteriorated Dissolution of Amorphous Itraconazole: Description of Incompatibility with Magnesium Stearate and Possible Solutions.
Authors: Démuth B; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Galata DL; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Szabó E; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Nagy B; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Farkas A; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Balogh A; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Hirsch E; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Pataki H; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Rapi Z; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Bezúr L; Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics (BME) , Szent Gellért tér 4, H-1111, Budapest, Hungary., Vigh T; Drug Product Development, Janssen R&D , Turnhoutseweg 30, B-2340 Beerse, Belgium., Verreck G; Drug Product Development, Janssen R&D , Turnhoutseweg 30, B-2340 Beerse, Belgium., Szalay Z; Drug Polymorphism Research, Gedeon Richter Plc. , Gyömrői út 30-32, H-1103 Budapest, Hungary., Demeter Á; Drug Polymorphism Research, Gedeon Richter Plc. , Gyömrői út 30-32, H-1103 Budapest, Hungary., Marosi G; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary., Nagy ZK; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME) , Műegyetem rkp. 3, H-1111 Budapest, Hungary.
Source: Molecular pharmaceutics [Mol Pharm] 2017 Nov 06; Vol. 14 (11), pp. 3927-3934. Date of Electronic Publication: 2017 Oct 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1543-8392
DOI:10.1021/acs.molpharmaceut.7b00629