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Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.

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Title: Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.
Authors: Boehm M; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Beaumont K; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Jones R; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Kalgutkar AS; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Zhang L; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Atkinson K; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Bai G; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Brown JA; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Eng H; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Goetz GH; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Holder BR; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Khunte B; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Lazzaro S; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Limberakis C; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Ryu S; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Shapiro MJ; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Tylaska L; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Yan J; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Turner R; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Leung SSF; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States.; Circle Pharma , South San Francisco, California 94080, United States., Ramaseshan M; Circle Pharma , South San Francisco, California 94080, United States., Price DA; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Liras S; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Jacobson MP; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States., Earp DJ; Circle Pharma , South San Francisco, California 94080, United States., Lokey RS; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Mathiowetz AM; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Menhaji-Klotz E; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9653-9663. Date of Electronic Publication: 2017 Oct 30.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.
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  Data: <searchLink fieldCode="AU" term="%22Boehm+M%22">Boehm M</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Beaumont+K%22">Beaumont K</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Jones+R%22">Jones R</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Kalgutkar+AS%22">Kalgutkar AS</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Atkinson+K%22">Atkinson K</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Bai+G%22">Bai G</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Brown+JA%22">Brown JA</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Eng+H%22">Eng H</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Goetz+GH%22">Goetz GH</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Holder+BR%22">Holder BR</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Khunte+B%22">Khunte B</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Lazzaro+S%22">Lazzaro S</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Limberakis+C%22">Limberakis C</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Ryu+S%22">Ryu S</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Shapiro+MJ%22">Shapiro MJ</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Tylaska+L%22">Tylaska L</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Turner+R%22">Turner R</searchLink>; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Leung+SSF%22">Leung SSF</searchLink>; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States.; Circle Pharma , South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Ramaseshan+M%22">Ramaseshan M</searchLink>; Circle Pharma , South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Price+DA%22">Price DA</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Liras+S%22">Liras S</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Jacobson+MP%22">Jacobson MP</searchLink>; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Earp+DJ%22">Earp DJ</searchLink>; Circle Pharma , South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Lokey+RS%22">Lokey RS</searchLink>; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Mathiowetz+AM%22">Mathiowetz AM</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Menhaji-Klotz+E%22">Menhaji-Klotz E</searchLink>; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9653-9663. <i>Date of Electronic Publication: </i>2017 Oct 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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