Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.
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| Title: | Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators. |
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| Authors: | Boehm M; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Beaumont K; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Jones R; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Kalgutkar AS; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Zhang L; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Atkinson K; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Bai G; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Brown JA; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Eng H; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Goetz GH; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Holder BR; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Khunte B; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Lazzaro S; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Limberakis C; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Ryu S; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Shapiro MJ; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Tylaska L; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Yan J; Pfizer Worldwide Research & Development , Groton, Connecticut 06340, United States., Turner R; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Leung SSF; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States.; Circle Pharma , South San Francisco, California 94080, United States., Ramaseshan M; Circle Pharma , South San Francisco, California 94080, United States., Price DA; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Liras S; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Jacobson MP; Department of Pharmaceutical Chemistry, University of California , San Francisco, California 94158, United States., Earp DJ; Circle Pharma , South San Francisco, California 94080, United States., Lokey RS; Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Mathiowetz AM; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States., Menhaji-Klotz E; Pfizer Worldwide Research & Development , Cambridge, Massachusetts 02139, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9653-9663. Date of Electronic Publication: 2017 Oct 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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