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Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.

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Title: Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.
Authors: Ibanez L; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Dube U; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.; Medical Scientist Training Program, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA., Saef B; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Budde J; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Black K; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Medvedeva A; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Del-Aguila JL; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Davis AA; Department of Neurology, School of Medicine, Washington University in St Louis, Saint Louis, MO, USA., Perlmutter JS; Department of Neurology, School of Medicine, Washington University in St Louis, Saint Louis, MO, USA., Harari O; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA., Benitez BA; Department of Medicine, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA., Cruchaga C; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA. cruchagac@wustl.edu.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA. cruchagac@wustl.edu.
Source: BMC neurology [BMC Neurol] 2017 Nov 15; Vol. 17 (1), pp. 198. Date of Electronic Publication: 2017 Nov 15.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2377 (Electronic) Linking ISSN: 14712377 NLM ISO Abbreviation: BMC Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.
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  Data: <searchLink fieldCode="AU" term="%22Ibanez+L%22">Ibanez L</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Dube+U%22">Dube U</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.; Medical Scientist Training Program, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Saef+B%22">Saef B</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Budde+J%22">Budde J</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Black+K%22">Black K</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Medvedeva+A%22">Medvedeva A</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Del-Aguila+JL%22">Del-Aguila JL</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Davis+AA%22">Davis AA</searchLink>; Department of Neurology, School of Medicine, Washington University in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Perlmutter+JS%22">Perlmutter JS</searchLink>; Department of Neurology, School of Medicine, Washington University in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Harari+O%22">Harari O</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Benitez+BA%22">Benitez BA</searchLink>; Department of Medicine, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA. cruchagac@wustl.edu.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University in Saint Louis, Saint Louis, MO, USA. cruchagac@wustl.edu.
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  Data: <searchLink fieldCode="JN" term="%22100968555%22">BMC neurology</searchLink> [BMC Neurol] 2017 Nov 15; Vol. 17 (1), pp. 198. <i>Date of Electronic Publication: </i>2017 Nov 15.
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