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Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.

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Title: Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
Authors: Jerome RN; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA. rebecca.jerome@vumc.org., Pulley JM; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Roden DM; Office of Research, Vanderbilt University Medical Center, Nashville, TN, USA., Shirey-Rice JK; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Bastarache LA; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA., R Bernard G; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Office of Research, Vanderbilt University Medical Center, Nashville, TN, USA., B Ekstrom L; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Nashville Biosciences, Nashville, TN, USA., Lancaster WJ; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA., Denny JC; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA.
Source: Drug safety [Drug Saf] 2018 Mar; Vol. 41 (3), pp. 303-311.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9002928 Publication Model: Print Cited Medium: Internet ISSN: 1179-1942 (Electronic) Linking ISSN: 01145916 NLM ISO Abbreviation: Drug Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Jerome+RN%22">Jerome RN</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA. rebecca.jerome@vumc.org.<br /><searchLink fieldCode="AU" term="%22Pulley+JM%22">Pulley JM</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; Office of Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Shirey-Rice+JK%22">Shirey-Rice JK</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Bastarache+LA%22">Bastarache LA</searchLink>; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22R+Bernard+G%22">R Bernard G</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Office of Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22B+Ekstrom+L%22">B Ekstrom L</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Nashville Biosciences, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Lancaster+WJ%22">Lancaster WJ</searchLink>; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9002928 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1942 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201145916%22">01145916 </searchLink><i>NLM ISO Abbreviation: </i>Drug Saf <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40264-017-0616-0
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        Text: English
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      – TitleFull: Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
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              Text: 2018 Mar
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