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Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity.

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Title: Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity.
Authors: He S; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA. shan.he@temple.edu., Liu Y; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Meng L; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Sun H; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Wang Y; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Ji Y; Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA., Purushe J; Department of Microbiology & Immunology, Temple University, Philadelphia, PA, 19140, USA., Chen P; The Division of Endocrinology and the Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, 19104, USA., Li C; The Division of Endocrinology and the Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, 19104, USA., Madzo J; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Issa JP; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Soboloff J; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA., Reshef R; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, 10032, USA., Moore B; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48105, USA., Gattinoni L; Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA., Zhang Y; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA. yi.zhang@temple.edu.; Department of Microbiology & Immunology, Temple University, Philadelphia, PA, 19140, USA. yi.zhang@temple.edu.
Source: Nature communications [Nat Commun] 2017 Dec 14; Vol. 8 (1), pp. 2125. Date of Electronic Publication: 2017 Dec 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Ezh2 phosphorylation state determines its capacity to maintain CD8<superscript>+</superscript> T memory precursors for antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22He+S%22">He S</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA. shan.he@temple.edu.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Meng+L%22">Meng L</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Ji+Y%22">Ji Y</searchLink>; Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Purushe+J%22">Purushe J</searchLink>; Department of Microbiology & Immunology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Chen+P%22">Chen P</searchLink>; The Division of Endocrinology and the Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; The Division of Endocrinology and the Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Madzo+J%22">Madzo J</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Issa+JP%22">Issa JP</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Soboloff+J%22">Soboloff J</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Reshef+R%22">Reshef R</searchLink>; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Moore+B%22">Moore B</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48105, USA.<br /><searchLink fieldCode="AU" term="%22Gattinoni+L%22">Gattinoni L</searchLink>; Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA, 19140, USA. yi.zhang@temple.edu.; Department of Microbiology & Immunology, Temple University, Philadelphia, PA, 19140, USA. yi.zhang@temple.edu.
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