Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.

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Title: Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.
Authors: Kitagawa M; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Liao PJ; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Lee KH; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Wong J; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Shang SC; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore., Minami N; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Sampetrean O; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Saya H; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Lingyun D; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Prabhu N; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Diam GK; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Sobota R; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore., Larsson A; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Nordlund P; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, SE-171 77, Sweden., McCormick F; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158-9001, USA., Ghosh S; Department of Cardiovascular and Metabolic Research, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, 27707, USA.; Program in Cardiovascular and Metabolic Disorders and Centre for Computational Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Epstein DM; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.; Center for Technology & Development (CTeD), Duke-NUS Medical School, Singapore, 169857, Singapore., Dymock BW; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore., Lee SH; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. sanghyun.lee@duke-nus.edu.sg.
Source: Nature communications [Nat Commun] 2017 Dec 19; Vol. 8 (1), pp. 2200. Date of Electronic Publication: 2017 Dec 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.
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  Data: <searchLink fieldCode="AU" term="%22Kitagawa+M%22">Kitagawa M</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Liao+PJ%22">Liao PJ</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+J%22">Wong J</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Shang+SC%22">Shang SC</searchLink>; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore.<br /><searchLink fieldCode="AU" term="%22Minami+N%22">Minami N</searchLink>; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan.<br /><searchLink fieldCode="AU" term="%22Sampetrean+O%22">Sampetrean O</searchLink>; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan.<br /><searchLink fieldCode="AU" term="%22Saya+H%22">Saya H</searchLink>; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan.<br /><searchLink fieldCode="AU" term="%22Lingyun+D%22">Lingyun D</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Prabhu+N%22">Prabhu N</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Diam+GK%22">Diam GK</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Sobota+R%22">Sobota R</searchLink>; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Larsson+A%22">Larsson A</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Nordlund+P%22">Nordlund P</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, SE-171 77, Sweden.<br /><searchLink fieldCode="AU" term="%22McCormick+F%22">McCormick F</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158-9001, USA.<br /><searchLink fieldCode="AU" term="%22Ghosh+S%22">Ghosh S</searchLink>; Department of Cardiovascular and Metabolic Research, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, 27707, USA.; Program in Cardiovascular and Metabolic Disorders and Centre for Computational Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Epstein+DM%22">Epstein DM</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.; Center for Technology & Development (CTeD), Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Dymock+BW%22">Dymock BW</searchLink>; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. sanghyun.lee@duke-nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2017 Dec 19; Vol. 8 (1), pp. 2200. <i>Date of Electronic Publication: </i>2017 Dec 19.
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