Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.
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| Title: | Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality. |
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| Authors: | Kitagawa M; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Liao PJ; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Lee KH; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Wong J; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Shang SC; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore., Minami N; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Sampetrean O; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Saya H; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-0082, Japan., Lingyun D; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Prabhu N; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Diam GK; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Sobota R; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore., Larsson A; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore., Nordlund P; School of Biological Sciences, Nanyang Technological University, Singapore, 138673, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, SE-171 77, Sweden., McCormick F; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158-9001, USA., Ghosh S; Department of Cardiovascular and Metabolic Research, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, 27707, USA.; Program in Cardiovascular and Metabolic Disorders and Centre for Computational Biology, Duke-NUS Medical School, Singapore, 169857, Singapore., Epstein DM; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.; Center for Technology & Development (CTeD), Duke-NUS Medical School, Singapore, 169857, Singapore., Dymock BW; Department of Pharmacy, National University of Singapore, Singapore, 117543, Singapore., Lee SH; Program in Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. sanghyun.lee@duke-nus.edu.sg. |
| Source: | Nature communications [Nat Commun] 2017 Dec 19; Vol. 8 (1), pp. 2200. Date of Electronic Publication: 2017 Dec 19. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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