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Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition.

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Title: Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition.
Authors: Dey J; Presage Biosciences, Inc, Seattle, WA, USA., Deckwerth TL; Presage Biosciences, Inc, Seattle, WA, USA., Kerwin WS; Presage Biosciences, Inc, Seattle, WA, USA., Casalini JR; Presage Biosciences, Inc, Seattle, WA, USA., Merrell AJ; Presage Biosciences, Inc, Seattle, WA, USA., Grenley MO; Presage Biosciences, Inc, Seattle, WA, USA., Burns C; Presage Biosciences, Inc, Seattle, WA, USA., Ditzler SH; Presage Biosciences, Inc, Seattle, WA, USA., Dixon CP; Presage Biosciences, Inc, Seattle, WA, USA., Beirne E; Presage Biosciences, Inc, Seattle, WA, USA., Gillespie KC; Presage Biosciences, Inc, Seattle, WA, USA., Kleinman EF; Edward F. Kleinman LLC, Pawcatuck, CT, USA., Klinghoffer RA; Presage Biosciences, Inc, Seattle, WA, USA. rich.klinghoffer@presagebio.com.
Source: Scientific reports [Sci Rep] 2017 Dec 21; Vol. 7 (1), pp. 18007. Date of Electronic Publication: 2017 Dec 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Dey+J%22">Dey J</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Deckwerth+TL%22">Deckwerth TL</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kerwin+WS%22">Kerwin WS</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Casalini+JR%22">Casalini JR</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Merrell+AJ%22">Merrell AJ</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Grenley+MO%22">Grenley MO</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Burns+C%22">Burns C</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ditzler+SH%22">Ditzler SH</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dixon+CP%22">Dixon CP</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Beirne+E%22">Beirne E</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Gillespie+KC%22">Gillespie KC</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kleinman+EF%22">Kleinman EF</searchLink>; Edward F. Kleinman LLC, Pawcatuck, CT, USA.<br /><searchLink fieldCode="AU" term="%22Klinghoffer+RA%22">Klinghoffer RA</searchLink>; Presage Biosciences, Inc, Seattle, WA, USA. rich.klinghoffer@presagebio.com.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2017 Dec 21; Vol. 7 (1), pp. 18007. <i>Date of Electronic Publication: </i>2017 Dec 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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