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Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.

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Title: Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Authors: Stefański T; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland. Electronic address: tstefanski@ump.edu.pl., Mikstacka R; Department of Inorganic and Analytical Chemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland., Kurczab R; Department of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland., Dutkiewicz Z; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland., Kucińska M; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland., Murias M; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland., Zielińska-Przyjemska M; Department of Pharmaceutical Biochemistry, Poznan University of Medical Sciences, Święcickiego 4, 60-781 Poznań, Poland., Cichocki M; Department of Pharmaceutical Biochemistry, Poznan University of Medical Sciences, Święcickiego 4, 60-781 Poznań, Poland., Teubert A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland., Kaczmarek M; Department of Immunology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznań, Poland., Hogendorf A; Department of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland., Sobiak S; Department of Inorganic and Analytical Chemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2018 Jan 20; Vol. 144, pp. 797-816. Date of Electronic Publication: 2017 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Stefański+T%22">Stefański T</searchLink>; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland. Electronic address: tstefanski@ump.edu.pl.<br /><searchLink fieldCode="AU" term="%22Mikstacka+R%22">Mikstacka R</searchLink>; Department of Inorganic and Analytical Chemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Kurczab+R%22">Kurczab R</searchLink>; Department of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Dutkiewicz+Z%22">Dutkiewicz Z</searchLink>; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Kucińska+M%22">Kucińska M</searchLink>; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Murias+M%22">Murias M</searchLink>; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Zielińska-Przyjemska+M%22">Zielińska-Przyjemska M</searchLink>; Department of Pharmaceutical Biochemistry, Poznan University of Medical Sciences, Święcickiego 4, 60-781 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Cichocki+M%22">Cichocki M</searchLink>; Department of Pharmaceutical Biochemistry, Poznan University of Medical Sciences, Święcickiego 4, 60-781 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Teubert+A%22">Teubert A</searchLink>; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Kaczmarek+M%22">Kaczmarek M</searchLink>; Department of Immunology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Hogendorf+A%22">Hogendorf A</searchLink>; Department of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Sobiak+S%22">Sobiak S</searchLink>; Department of Inorganic and Analytical Chemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland.
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  Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2018 Jan 20; Vol. 144, pp. 797-816. <i>Date of Electronic Publication: </i>2017 Dec 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE
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