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Dual Allosteric Inhibition of SHP2 Phosphatase.

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Title: Dual Allosteric Inhibition of SHP2 Phosphatase.
Authors: Fodor M; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Price E; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Wang P; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Lu H; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Argintaru A; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Chen Z; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Glick M; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Hao HX; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Kato M; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Koenig R; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., LaRochelle JR; Department of Biological Chemistry & Molecular Pharmacology , Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States., Liu G; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., McNeill E; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Majumdar D; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Nishiguchi GA; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Perez LB; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Paris G; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Quinn CM; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Ramsey T; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Sendzik M; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Shultz MD; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Williams SL; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Stams T; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., Blacklow SC; Department of Biological Chemistry & Molecular Pharmacology , Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States., Acker MG; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States., LaMarche MJ; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States.
Source: ACS chemical biology [ACS Chem Biol] 2018 Mar 16; Vol. 13 (3), pp. 647-656. Date of Electronic Publication: 2018 Jan 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101282906%22">ACS chemical biology</searchLink> [ACS Chem Biol] 2018 Mar 16; Vol. 13 (3), pp. 647-656. <i>Date of Electronic Publication: </i>2018 Jan 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101282906 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1554-8937 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215548929%22">15548929 </searchLink><i>NLM ISO Abbreviation: </i>ACS Chem Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acschembio.7b00980
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