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Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex.

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Title: Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex.
Authors: Perego J; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Mendes A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France., Bourbon C; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Camosseto V; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France., Combes A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Liu H; Sanofi, Cambridge, MA 02139, USA., Manh TV; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Dalet A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Chasson L; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Spinelli L; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Bardin N; Laboratoire d'Immunologie, Hôpital de la Conception, 13005 Marseille, France.; Aix Marseille Université, INSERM, VRCM, 13005 Marseille, France., Chiche L; Hôpital Européen, 13003 Marseille, France., Santos MAS; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal., Gatti E; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal., Pierre P; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal.
Source: Science signaling [Sci Signal] 2018 Jan 23; Vol. 11 (514). Date of Electronic Publication: 2018 Jan 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex.
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  Data: <searchLink fieldCode="AU" term="%22Perego+J%22">Perego J</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Mendes+A%22">Mendes A</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Bourbon+C%22">Bourbon C</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Camosseto+V%22">Camosseto V</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Combes+A%22">Combes A</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Sanofi, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Manh+TV%22">Manh TV</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Dalet+A%22">Dalet A</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Chasson+L%22">Chasson L</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Spinelli+L%22">Spinelli L</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Bardin+N%22">Bardin N</searchLink>; Laboratoire d'Immunologie, Hôpital de la Conception, 13005 Marseille, France.; Aix Marseille Université, INSERM, VRCM, 13005 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Chiche+L%22">Chiche L</searchLink>; Hôpital Européen, 13003 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Santos+MAS%22">Santos MAS</searchLink>; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Gatti+E%22">Gatti E</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Pierre+P%22">Pierre P</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal.
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