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Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer.

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Title: Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer.
Authors: Mohammad AS; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Griffith JI; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Adkins CE; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Shah N; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Sechrest E; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Dolan EL; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Terrell-Hall TB; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA., Hendriks BS; Merrimack Pharmaceuticals, Cambridge, Massachusetts, 02139, USA., Lee H; Merrimack Pharmaceuticals, Cambridge, Massachusetts, 02139, USA., Lockman PR; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA. prlockman@hsc.wvu.edu.
Source: Pharmaceutical research [Pharm Res] 2018 Jan 09; Vol. 35 (2), pp. 31. Date of Electronic Publication: 2018 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Mohammad+AS%22">Mohammad AS</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Griffith+JI%22">Griffith JI</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Adkins+CE%22">Adkins CE</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Shah+N%22">Shah N</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Sechrest+E%22">Sechrest E</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Dolan+EL%22">Dolan EL</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Terrell-Hall+TB%22">Terrell-Hall TB</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA.<br /><searchLink fieldCode="AU" term="%22Hendriks+BS%22">Hendriks BS</searchLink>; Merrimack Pharmaceuticals, Cambridge, Massachusetts, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Merrimack Pharmaceuticals, Cambridge, Massachusetts, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Lockman+PR%22">Lockman PR</searchLink>; School of Pharmacy, Department of Pharmaceutical Sciences, West Virginia University Health Sciences Center, 1 Medical Center Drive, Morgantown, West Virginia, 26506-9050, USA. prlockman@hsc.wvu.edu.
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  Data: <searchLink fieldCode="JN" term="%228406521%22">Pharmaceutical research</searchLink> [Pharm Res] 2018 Jan 09; Vol. 35 (2), pp. 31. <i>Date of Electronic Publication: </i>2018 Jan 09.
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