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Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.

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Title: Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.
Authors: Chalmers SA; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA., Wen J; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA., Doerner J; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA., Stock A; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA., Cuda CM; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Makinde HM; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Perlman H; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Bosanac T; Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Webb D; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Nabozny G; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Fine JS; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Klein E; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Ramanujam M; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA., Putterman C; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA. chaim.putterman@einstein.yu.edu.; Division of Rheumatology, Albert Einstein College of Medicine, F701N, 1300 Morris Park Ave, Bronx, NY, 10461, USA. chaim.putterman@einstein.yu.edu.
Source: Arthritis research & therapy [Arthritis Res Ther] 2018 Jan 25; Vol. 20 (1), pp. 10. Date of Electronic Publication: 2018 Jan 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.
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  Data: <searchLink fieldCode="AU" term="%22Chalmers+SA%22">Chalmers SA</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wen+J%22">Wen J</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Doerner+J%22">Doerner J</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stock+A%22">Stock A</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cuda+CM%22">Cuda CM</searchLink>; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Makinde+HM%22">Makinde HM</searchLink>; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Perlman+H%22">Perlman H</searchLink>; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bosanac+T%22">Bosanac T</searchLink>; Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Webb+D%22">Webb D</searchLink>; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Nabozny+G%22">Nabozny G</searchLink>; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Fine+JS%22">Fine JS</searchLink>; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Klein+E%22">Klein E</searchLink>; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Ramanujam+M%22">Ramanujam M</searchLink>; Immunology and Respiratory Disease Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Putterman+C%22">Putterman C</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA. chaim.putterman@einstein.yu.edu.; Division of Rheumatology, Albert Einstein College of Medicine, F701N, 1300 Morris Park Ave, Bronx, NY, 10461, USA. chaim.putterman@einstein.yu.edu.
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