View in EDS

Activity and Safety of Cetuximab Plus Modified FOLFOXIRI Followed by Maintenance With Cetuximab or Bevacizumab for RAS and BRAF Wild-type Metastatic Colorectal Cancer: A Randomized Phase 2 Clinical Trial.

Saved in:
Bibliographic Details
Title: Activity and Safety of Cetuximab Plus Modified FOLFOXIRI Followed by Maintenance With Cetuximab or Bevacizumab for RAS and BRAF Wild-type Metastatic Colorectal Cancer: A Randomized Phase 2 Clinical Trial.
Authors: Cremolini C; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy., Antoniotti C; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy., Lonardi S; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy., Aprile G; Department of Oncology, University and General Hospital, Udine, Italy.; Department of Oncology, San Bortolo General Hospital, ULSS8 Berica, East District, Vicenza, Italy., Bergamo F; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy., Masi G; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy., Grande R; Department of Medical Oncology, Hospital of Frosinone, Frosinone, Italy., Tonini G; Dipartimento di Oncologia Università Campus Bio-Medico di Roma, Rome, Italy., Mescoli C; Surgical Pathology and Cytopathology Unit, Department of Medicine, University of Padua, Padova, Italy., Cardellino GG; Department of Oncology, University and General Hospital, Udine, Italy., Coltelli L; Unit of Medical Oncology, Hospital Felice Lotti, Azienda Toscana Nord Ovest, Pontedera, Italy., Salvatore L; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.; Unit of Medical Oncology, Policlinico G. B. Rossi, Azienda Ospedaliera Integrata di Verona, Verona, Italy., Corsi DC; Unit of Medical Oncology, Hospital San Giovanni Calibita Fatebenefratelli, Rome, Italy., Lupi C; Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy., Gemma D; Department of Medical Oncology, Hospital of Frosinone, Frosinone, Italy., Ronzoni M; Department of Oncology, Hospital San Raffaele IRCSS, Milan, Italy., Dell'Aquila E; Dipartimento di Oncologia Università Campus Bio-Medico di Roma, Rome, Italy., Marmorino F; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy., Di Fabio F; Unit of Medical Oncology, Policlinico Sant'Orsola-Malpighi, Bologna, Italy., Mancini ML; Department of Medical Oncology, Policlinico Umberto I Sapienza, University of Rome, Rome, Italy., Marcucci L; Unit of Medical Oncology, Hospital Felice Lotti, Azienda Toscana Nord Ovest, Pontedera, Italy., Fontanini G; Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy., Zagonel V; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy., Boni L; Clinical Trials Coordinating Center, Toscano Cancer Institute, University Hospital Careggi, Florence, Italy., Falcone A; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.
Source: JAMA oncology [JAMA Oncol] 2018 Apr 01; Vol. 4 (4), pp. 529-536.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101652861 Publication Model: Print Cited Medium: Internet ISSN: 2374-2445 (Electronic) Linking ISSN: 23742437 NLM ISO Abbreviation: JAMA Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 29450468
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Activity and Safety of Cetuximab Plus Modified FOLFOXIRI Followed by Maintenance With Cetuximab or Bevacizumab for RAS and BRAF Wild-type Metastatic Colorectal Cancer: A Randomized Phase 2 Clinical Trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Cremolini+C%22">Cremolini C</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Antoniotti+C%22">Antoniotti C</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Lonardi+S%22">Lonardi S</searchLink>; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Aprile+G%22">Aprile G</searchLink>; Department of Oncology, University and General Hospital, Udine, Italy.; Department of Oncology, San Bortolo General Hospital, ULSS8 Berica, East District, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Bergamo+F%22">Bergamo F</searchLink>; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Masi+G%22">Masi G</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Grande+R%22">Grande R</searchLink>; Department of Medical Oncology, Hospital of Frosinone, Frosinone, Italy.<br /><searchLink fieldCode="AU" term="%22Tonini+G%22">Tonini G</searchLink>; Dipartimento di Oncologia Università Campus Bio-Medico di Roma, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mescoli+C%22">Mescoli C</searchLink>; Surgical Pathology and Cytopathology Unit, Department of Medicine, University of Padua, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Cardellino+GG%22">Cardellino GG</searchLink>; Department of Oncology, University and General Hospital, Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Coltelli+L%22">Coltelli L</searchLink>; Unit of Medical Oncology, Hospital Felice Lotti, Azienda Toscana Nord Ovest, Pontedera, Italy.<br /><searchLink fieldCode="AU" term="%22Salvatore+L%22">Salvatore L</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.; Unit of Medical Oncology, Policlinico G. B. Rossi, Azienda Ospedaliera Integrata di Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Corsi+DC%22">Corsi DC</searchLink>; Unit of Medical Oncology, Hospital San Giovanni Calibita Fatebenefratelli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Lupi+C%22">Lupi C</searchLink>; Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Gemma+D%22">Gemma D</searchLink>; Department of Medical Oncology, Hospital of Frosinone, Frosinone, Italy.<br /><searchLink fieldCode="AU" term="%22Ronzoni+M%22">Ronzoni M</searchLink>; Department of Oncology, Hospital San Raffaele IRCSS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dell'Aquila+E%22">Dell'Aquila E</searchLink>; Dipartimento di Oncologia Università Campus Bio-Medico di Roma, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Marmorino+F%22">Marmorino F</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Fabio+F%22">Di Fabio F</searchLink>; Unit of Medical Oncology, Policlinico Sant'Orsola-Malpighi, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mancini+ML%22">Mancini ML</searchLink>; Department of Medical Oncology, Policlinico Umberto I Sapienza, University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Marcucci+L%22">Marcucci L</searchLink>; Unit of Medical Oncology, Hospital Felice Lotti, Azienda Toscana Nord Ovest, Pontedera, Italy.<br /><searchLink fieldCode="AU" term="%22Fontanini+G%22">Fontanini G</searchLink>; Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Zagonel+V%22">Zagonel V</searchLink>; Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto-IRCCS, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Boni+L%22">Boni L</searchLink>; Clinical Trials Coordinating Center, Toscano Cancer Institute, University Hospital Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Falcone+A%22">Falcone A</searchLink>; Unit of Medical Oncology 2, Department of Translational Research and New Technologies in Medicine and Surgery, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Pisa, Italy.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101652861%22">JAMA oncology</searchLink> [JAMA Oncol] 2018 Apr 01; Vol. 4 (4), pp. 529-536.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101652861 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2374-2445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223742437%22">23742437 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Oncol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29450468
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1001/jamaoncol.2017.5314
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 529
    Titles:
      – TitleFull: Activity and Safety of Cetuximab Plus Modified FOLFOXIRI Followed by Maintenance With Cetuximab or Bevacizumab for RAS and BRAF Wild-type Metastatic Colorectal Cancer: A Randomized Phase 2 Clinical Trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Cremolini C
      – PersonEntity:
          Name:
            NameFull: Antoniotti C
      – PersonEntity:
          Name:
            NameFull: Lonardi S
      – PersonEntity:
          Name:
            NameFull: Aprile G
      – PersonEntity:
          Name:
            NameFull: Bergamo F
      – PersonEntity:
          Name:
            NameFull: Masi G
      – PersonEntity:
          Name:
            NameFull: Grande R
      – PersonEntity:
          Name:
            NameFull: Tonini G
      – PersonEntity:
          Name:
            NameFull: Mescoli C
      – PersonEntity:
          Name:
            NameFull: Cardellino GG
      – PersonEntity:
          Name:
            NameFull: Coltelli L
      – PersonEntity:
          Name:
            NameFull: Salvatore L
      – PersonEntity:
          Name:
            NameFull: Corsi DC
      – PersonEntity:
          Name:
            NameFull: Lupi C
      – PersonEntity:
          Name:
            NameFull: Gemma D
      – PersonEntity:
          Name:
            NameFull: Ronzoni M
      – PersonEntity:
          Name:
            NameFull: Dell'Aquila E
      – PersonEntity:
          Name:
            NameFull: Marmorino F
      – PersonEntity:
          Name:
            NameFull: Di Fabio F
      – PersonEntity:
          Name:
            NameFull: Mancini ML
      – PersonEntity:
          Name:
            NameFull: Marcucci L
      – PersonEntity:
          Name:
            NameFull: Fontanini G
      – PersonEntity:
          Name:
            NameFull: Zagonel V
      – PersonEntity:
          Name:
            NameFull: Boni L
      – PersonEntity:
          Name:
            NameFull: Falcone A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2018 Apr 01
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 2374-2445
          Numbering:
            – Type: volume
              Value: 4
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: JAMA oncology
              Type: main
ResultId 1