Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

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Title: Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.
Authors: Corbin LJ; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Tan VY; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Hughes DA; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Wade KH; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Paul DS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation (BHF) Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Tansey KE; Core Bioinformatics and Statistics Team, College of Biomedical & Life Sciences, Cardiff University, Cardiff, CF10 3XQ, UK., Butcher F; Oxford School of Public Health, University of Oxford, Oxford, OX3 7LF, UK., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK., Howson JM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Jallow MW; Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.; MRC Unit The Gambia (MRCG), Atlantic Boulevard, Fajara, P.O. Box 273, Banjul, Gambia., John C; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK., Kingston N; National Institute for Health Research (NIHR) BioResource for Translational Research in Common and Rare Diseases & NIHR BioResource Centre Cambridge, University of Cambridge, Cambridge, CB2 0QQ, UK., Lindgren CM; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7FZ, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, 02142, USA.; NIHR Oxford Biomedical Research Centre, OUH Hospital, Oxford, OX4 2PG, UK., O'Donavan M; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, CF24 4HQ, UK., O'Rahilly S; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, CF24 4HQ, UK., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Pearson ER; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Scott RA; Quantitative Sciences, GlaxoSmithKline, Stevenage, SG1 2NY, UK., van Heel DA; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK., Whittaker J; Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.; Statistical Genetics, Projects, Clinical Platforms, and Sciences (PCPS), GlaxoSmithKline, Research Triangle Park, NC, 27709, USA., Frayling T; Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, EX1 2LU, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., Smith GD; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Evans DM; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.; The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, 4072, Australia., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation (BHF) Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0SR, UK., Franks PW; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, SE-205 02, Sweden.; Department of Public Health and Clinical Medicine, Section for Medicine, Umeå University, Umeå, 907 37, Sweden.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Timpson NJ; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK. n.j.timpson@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK. n.j.timpson@bristol.ac.uk.
Source: Nature communications [Nat Commun] 2018 Feb 19; Vol. 9 (1), pp. 711. Date of Electronic Publication: 2018 Feb 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Corbin+LJ%22">Corbin LJ</searchLink>; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Tan+VY%22">Tan VY</searchLink>; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+DA%22">Hughes DA</searchLink>; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Wade+KH%22">Wade KH</searchLink>; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Paul+DS%22">Paul DS</searchLink>; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation (BHF) Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Tansey+KE%22">Tansey KE</searchLink>; Core Bioinformatics and Statistics Team, College of Biomedical & Life Sciences, Cardiff University, Cardiff, CF10 3XQ, UK.<br /><searchLink fieldCode="AU" term="%22Butcher+F%22">Butcher F</searchLink>; Oxford School of Public Health, University of Oxford, Oxford, OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Dudbridge+F%22">Dudbridge F</searchLink>; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.<br /><searchLink fieldCode="AU" term="%22Howson+JM%22">Howson JM</searchLink>; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.<br /><searchLink fieldCode="AU" term="%22Jallow+MW%22">Jallow MW</searchLink>; Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.; MRC Unit The Gambia (MRCG), Atlantic Boulevard, Fajara, P.O. 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Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, SE-205 02, Sweden.; Department of Public Health and Clinical Medicine, Section for Medicine, Umeå University, Umeå, 907 37, Sweden.; Department of Nutrition, Harvard T.H. 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