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Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.

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Title: Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.
Authors: Chorzalska A; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Ahsan N; Division of Biology and Medicine, COBRE CCRD Proteomics Core Facility, Rhode Island Hospital, Brown University, Providence, RI, USA., Rao RSP; Division of Biostatistics and Bioinformatics, Yenepoya Research Center, Yenepoya University, Mangalore, India., Roder K; Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Yu X; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA., Morgan J; Flow Cytometry and Cell Sorting Core Facility, Roger Williams Medical Center, Providence, RI, USA., Tepper A; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Hines S; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Zhang P; Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Treaba DO; Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Zhao TC; Cardiovascular Lab, Department of Surgery, Roger Williams Medical Center, Boston University School of Medicine, Providence, RI, USA., Olszewski AJ; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Reagan JL; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Liang O; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA., Gruppuso PA; Department of Pediatrics, Rhode Island Hospital, Brown University, Providence, RI, USA., Dubielecka PM; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Source: Molecular oncology [Mol Oncol] 2018 May; Vol. 12 (5), pp. 630-647. Date of Electronic Publication: 2018 Apr 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Chorzalska+A%22">Chorzalska A</searchLink>; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Ahsan+N%22">Ahsan N</searchLink>; Division of Biology and Medicine, COBRE CCRD Proteomics Core Facility, Rhode Island Hospital, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Rao+RSP%22">Rao RSP</searchLink>; Division of Biostatistics and Bioinformatics, Yenepoya Research Center, Yenepoya University, Mangalore, India.<br /><searchLink fieldCode="AU" term="%22Roder+K%22">Roder K</searchLink>; Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+J%22">Morgan J</searchLink>; Flow Cytometry and Cell Sorting Core Facility, Roger Williams Medical Center, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Tepper+A%22">Tepper A</searchLink>; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Hines+S%22">Hines S</searchLink>; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Treaba+DO%22">Treaba DO</searchLink>; Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+TC%22">Zhao TC</searchLink>; Cardiovascular Lab, Department of Surgery, Roger Williams Medical Center, Boston University School of Medicine, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Olszewski+AJ%22">Olszewski AJ</searchLink>; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Reagan+JL%22">Reagan JL</searchLink>; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Liang+O%22">Liang O</searchLink>; Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Gruppuso+PA%22">Gruppuso PA</searchLink>; Department of Pediatrics, Rhode Island Hospital, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Dubielecka+PM%22">Dubielecka PM</searchLink>; Signal Transduction Lab, Division of Hematology/Oncology, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, USA.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2018 May; Vol. 12 (5), pp. 630-647. <i>Date of Electronic Publication: </i>2018 Apr 06.
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