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Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.

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Title: Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.
Authors: Vatner DF; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. daniel.vatner@yale.edu., Goedeke L; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Camporez JG; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Lyu K; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA., Nasiri AR; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Zhang D; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA., Bhanot S; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA., Murray SF; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA., Still CD; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA., Gerhard GS; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA., Shulman GI; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA., Samuel VT; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. varman.samuel@yale.edu.; Veterans Affairs Medical Center, 950 Campbell Ave, BLG 5 3rd floor, West Haven, CT, 06516, USA. varman.samuel@yale.edu.
Source: Diabetologia [Diabetologia] 2018 Jun; Vol. 61 (6), pp. 1435-1446. Date of Electronic Publication: 2018 Mar 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.
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  Data: <searchLink fieldCode="AU" term="%22Vatner+DF%22">Vatner DF</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. daniel.vatner@yale.edu.<br /><searchLink fieldCode="AU" term="%22Goedeke+L%22">Goedeke L</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Camporez+JG%22">Camporez JG</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Lyu+K%22">Lyu K</searchLink>; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Nasiri+AR%22">Nasiri AR</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Bhanot+S%22">Bhanot S</searchLink>; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA.<br /><searchLink fieldCode="AU" term="%22Murray+SF%22">Murray SF</searchLink>; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA.<br /><searchLink fieldCode="AU" term="%22Still+CD%22">Still CD</searchLink>; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Gerhard+GS%22">Gerhard GS</searchLink>; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Shulman+GI%22">Shulman GI</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Samuel+VT%22">Samuel VT</searchLink>; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. varman.samuel@yale.edu.; Veterans Affairs Medical Center, 950 Campbell Ave, BLG 5 3rd floor, West Haven, CT, 06516, USA. varman.samuel@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%220006777%22">Diabetologia</searchLink> [Diabetologia] 2018 Jun; Vol. 61 (6), pp. 1435-1446. <i>Date of Electronic Publication: </i>2018 Mar 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0006777 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0428 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220012186X%22">0012186X </searchLink><i>NLM ISO Abbreviation: </i>Diabetologia <i>Subsets: </i>MEDLINE
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