Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.
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| Title: | Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents. |
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| Authors: | Vatner DF; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. daniel.vatner@yale.edu., Goedeke L; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Camporez JG; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Lyu K; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA., Nasiri AR; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA., Zhang D; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA., Bhanot S; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA., Murray SF; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA., Still CD; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA., Gerhard GS; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA., Shulman GI; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA., Samuel VT; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. varman.samuel@yale.edu.; Veterans Affairs Medical Center, 950 Campbell Ave, BLG 5 3rd floor, West Haven, CT, 06516, USA. varman.samuel@yale.edu. |
| Source: | Diabetologia [Diabetologia] 2018 Jun; Vol. 61 (6), pp. 1435-1446. Date of Electronic Publication: 2018 Mar 01. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0428 |
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| DOI: | 10.1007/s00125-018-4579-1 |
