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Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.

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Title: Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.
Authors: Maden CH; Projects Clinical Platforms and Sciences, GSK, Uxbridge, Middlesex, UK., Fairman D; Clinical Pharmacology Modelling and Simulation, GSK, Stevenage, Hertfordshire, UK., Chalker M; Global Clinical Safety and Pharmacovigilance, GSK, Uxbridge, Middlesex, UK., Costa MJ; Clinical Statistics, GSK, Stevenage, Hertfordshire, UK., Fahy WA; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK., Garman N; Projects Clinical Platforms and Sciences, GSK, Uxbridge, Middlesex, UK., Lukey PT; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK., Mant T; QuintilesIMS, Reading, Berkshire, UK., Parry S; Platform Technology and Science, GSK, Ware, Hertfordshire, UK., Simpson JK; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK., Slack RJ; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK., Kendrick S; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK., Marshall RP; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK. richard.p.marshall@gsk.com.
Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2018 Jun; Vol. 74 (6), pp. 701-709. Date of Electronic Publication: 2018 Mar 12.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.
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  Data: <searchLink fieldCode="AU" term="%22Maden+CH%22">Maden CH</searchLink>; Projects Clinical Platforms and Sciences, GSK, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Fairman+D%22">Fairman D</searchLink>; Clinical Pharmacology Modelling and Simulation, GSK, Stevenage, Hertfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Chalker+M%22">Chalker M</searchLink>; Global Clinical Safety and Pharmacovigilance, GSK, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Costa+MJ%22">Costa MJ</searchLink>; Clinical Statistics, GSK, Stevenage, Hertfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Fahy+WA%22">Fahy WA</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Garman+N%22">Garman N</searchLink>; Projects Clinical Platforms and Sciences, GSK, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Lukey+PT%22">Lukey PT</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Mant+T%22">Mant T</searchLink>; QuintilesIMS, Reading, Berkshire, UK.<br /><searchLink fieldCode="AU" term="%22Parry+S%22">Parry S</searchLink>; Platform Technology and Science, GSK, Ware, Hertfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Simpson+JK%22">Simpson JK</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Slack+RJ%22">Slack RJ</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Kendrick+S%22">Kendrick S</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Marshall+RP%22">Marshall RP</searchLink>; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, SG1 2NY, UK. richard.p.marshall@gsk.com.
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  Data: <searchLink fieldCode="JN" term="%221256165%22">European journal of clinical pharmacology</searchLink> [Eur J Clin Pharmacol] 2018 Jun; Vol. 74 (6), pp. 701-709. <i>Date of Electronic Publication: </i>2018 Mar 12.
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