Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer.
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| Title: | Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer. |
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| Authors: | Patel N; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Weekes D; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Drosopoulos K; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK., Gazinska P; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Noel E; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Rashid M; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Mirza H; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK., Quist J; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK., Brasó-Maristany F; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Mathew S; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Ferro R; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Pereira AM; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Prince C; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Noor F; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Francesch-Domenech E; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Marlow R; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., de Rinaldis E; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Precision Immunology Cluster, Sanofi, 640 Memorial Drive, Cambridge, MA, 02149, USA., Grigoriadis A; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK., Linardopoulos S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK., Marra P; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK., Tutt ANJ; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK. andrew.tutt@icr.ac.uk.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK. andrew.tutt@icr.ac.uk.; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK. andrew.tutt@icr.ac.uk. |
| Source: | Nature communications [Nat Commun] 2018 Mar 13; Vol. 9 (1), pp. 1044. Date of Electronic Publication: 2018 Mar 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29535384 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Patel+N%22">Patel N</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Weekes+D%22">Weekes D</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Drosopoulos+K%22">Drosopoulos K</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.<br /><searchLink fieldCode="AU" term="%22Gazinska+P%22">Gazinska P</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Noel+E%22">Noel E</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Rashid+M%22">Rashid M</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Mirza+H%22">Mirza H</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Quist+J%22">Quist J</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Brasó-Maristany+F%22">Brasó-Maristany F</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Mathew+S%22">Mathew S</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Ferro+R%22">Ferro R</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Pereira+AM%22">Pereira AM</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Prince+C%22">Prince C</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Noor+F%22">Noor F</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Francesch-Domenech+E%22">Francesch-Domenech E</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Marlow+R%22">Marlow R</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22de+Rinaldis+E%22">de Rinaldis E</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Precision Immunology Cluster, Sanofi, 640 Memorial Drive, Cambridge, MA, 02149, USA.<br /><searchLink fieldCode="AU" term="%22Grigoriadis+A%22">Grigoriadis A</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.; Cancer Bioinformatics, King's College London, London, SE1 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Linardopoulos+S%22">Linardopoulos S</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK.<br /><searchLink fieldCode="AU" term="%22Marra+P%22">Marra P</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Tutt+ANJ%22">Tutt ANJ</searchLink>; Breast Cancer Now Research Unit, King's College London, London, SE1 9RT, UK. andrew.tutt@icr.ac.uk.; School of Cancer and Pharmaceutical Sciences, King's Health Partners AHSC, Faculty of Life Sciences and Medicine, King's College London, London, WC2R 2LS, UK. andrew.tutt@icr.ac.uk.; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK. andrew.tutt@icr.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Mar 13; Vol. 9 (1), pp. 1044. <i>Date of Electronic Publication: </i>2018 Mar 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-018-03283-z Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1044 Titles: – TitleFull: Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Patel N – PersonEntity: Name: NameFull: Weekes D – PersonEntity: Name: NameFull: Drosopoulos K – PersonEntity: Name: NameFull: Gazinska P – PersonEntity: Name: NameFull: Noel E – PersonEntity: Name: NameFull: Rashid M – PersonEntity: Name: NameFull: Mirza H – PersonEntity: Name: NameFull: Quist J – PersonEntity: Name: NameFull: Brasó-Maristany F – PersonEntity: Name: NameFull: Mathew S – PersonEntity: Name: NameFull: Ferro R – PersonEntity: Name: NameFull: Pereira AM – PersonEntity: Name: NameFull: Prince C – PersonEntity: Name: NameFull: Noor F – PersonEntity: Name: NameFull: Francesch-Domenech E – PersonEntity: Name: NameFull: Marlow R – PersonEntity: Name: NameFull: de Rinaldis E – PersonEntity: Name: NameFull: Grigoriadis A – PersonEntity: Name: NameFull: Linardopoulos S – PersonEntity: Name: NameFull: Marra P – PersonEntity: Name: NameFull: Tutt ANJ IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 03 Text: 2018 Mar 13 Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 2041-1723 Numbering: – Type: volume Value: 9 – Type: issue Value: 1 Titles: – TitleFull: Nature communications Type: main |
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