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Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.

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Title: Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.
Authors: Ogbechi J; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK., Hall BS; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK., Sbarrato T; MRC Toxicology Unit, Lancaster Rd, Leicester, LE1 9HN, UK., Taunton J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Willis AE; MRC Toxicology Unit, Lancaster Rd, Leicester, LE1 9HN, UK., Wek RC; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Simmonds RE; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK. rachel.simmonds@surrey.ac.uk.
Source: Cell death & disease [Cell Death Dis] 2018 Mar 14; Vol. 9 (3), pp. 397. Date of Electronic Publication: 2018 Mar 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.
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  Data: <searchLink fieldCode="AU" term="%22Ogbechi+J%22">Ogbechi J</searchLink>; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.<br /><searchLink fieldCode="AU" term="%22Hall+BS%22">Hall BS</searchLink>; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.<br /><searchLink fieldCode="AU" term="%22Sbarrato+T%22">Sbarrato T</searchLink>; MRC Toxicology Unit, Lancaster Rd, Leicester, LE1 9HN, UK.<br /><searchLink fieldCode="AU" term="%22Taunton+J%22">Taunton J</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Willis+AE%22">Willis AE</searchLink>; MRC Toxicology Unit, Lancaster Rd, Leicester, LE1 9HN, UK.<br /><searchLink fieldCode="AU" term="%22Wek+RC%22">Wek RC</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Simmonds+RE%22">Simmonds RE</searchLink>; Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK. rachel.simmonds@surrey.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2018 Mar 14; Vol. 9 (3), pp. 397. <i>Date of Electronic Publication: </i>2018 Mar 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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