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Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

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Title: Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.
Authors: Zengini E; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.; 5th Psychiatric Department, Dromokaiteio Psychiatric Hospital, Athens, Greece., Hatzikotoulas K; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Tachmazidou I; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; GSK, R&D Target Sciences, Medicines Research Centre, Stevenage, UK., Steinberg J; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Cancer Research Division, Cancer Council NSW, Sydney, New South Wales, Australia., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Southam L; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Hackinger S; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Boer CG; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Styrkarsdottir U; deCODE genetics/Amgen, Reykjavik, Iceland., Gilly A; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Suveges D; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Killian B; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Ingvarsson T; Department of Orthopaedic Surgery, Akureyri Hospital, Akureyri, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Institution of Health Science, University of Akureyri, Akureyri, Iceland., Jonsson H; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland., Babis GC; 2nd Department of Orthopaedic Surgery, Konstantopouleio General Hospital, National and Kapodistrian University of Athens, Athens, Greece., McCaskie A; Division of Trauma & Orthopaedic Surgery, Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Uitterlinden AG; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands., van Meurs JBJ; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Thorsteinsdottir U; deCODE genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Davey Smith G; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, University of Bristol, Bristol, UK.; National Institute for Health Research, Bristol Biomedical Research Centre, University Hospitals Bristol, NHS Foundation Trust and University of Bristol, Bristol, UK., Wilkinson JM; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Zeggini E; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK. eleftheria@sanger.ac.uk.
Source: Nature genetics [Nat Genet] 2018 Apr; Vol. 50 (4), pp. 549-558. Date of Electronic Publication: 2018 Mar 20.
Publication Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zengini+E%22">Zengini E</searchLink>; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.; 5th Psychiatric Department, Dromokaiteio Psychiatric Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Hatzikotoulas+K%22">Hatzikotoulas K</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Tachmazidou+I%22">Tachmazidou I</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; GSK, R&D Target Sciences, Medicines Research Centre, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Steinberg+J%22">Steinberg J</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Cancer Research Division, Cancer Council NSW, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hartwig+FP%22">Hartwig FP</searchLink>; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Southam+L%22">Southam L</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hackinger+S%22">Hackinger S</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Boer+CG%22">Boer CG</searchLink>; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Styrkarsdottir+U%22">Styrkarsdottir U</searchLink>; deCODE genetics/Amgen, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Gilly+A%22">Gilly A</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Suveges+D%22">Suveges D</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Killian+B%22">Killian B</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Ingvarsson+T%22">Ingvarsson T</searchLink>; Department of Orthopaedic Surgery, Akureyri Hospital, Akureyri, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Institution of Health Science, University of Akureyri, Akureyri, Iceland.<br /><searchLink fieldCode="AU" term="%22Jonsson+H%22">Jonsson H</searchLink>; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Babis+GC%22">Babis GC</searchLink>; 2nd Department of Orthopaedic Surgery, Konstantopouleio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22McCaskie+A%22">McCaskie A</searchLink>; Division of Trauma & Orthopaedic Surgery, Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Uitterlinden+AG%22">Uitterlinden AG</searchLink>; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Meurs+JBJ%22">van Meurs JBJ</searchLink>; Departments of Internal Medicine and Epidemiology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thorsteinsdottir+U%22">Thorsteinsdottir U</searchLink>; deCODE genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Davey+Smith+G%22">Davey Smith G</searchLink>; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, University of Bristol, Bristol, UK.; National Institute for Health Research, Bristol Biomedical Research Centre, University Hospitals Bristol, NHS Foundation Trust and University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Wilkinson+JM%22">Wilkinson JM</searchLink>; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Zeggini+E%22">Zeggini E</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK. eleftheria@sanger.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2018 Apr; Vol. 50 (4), pp. 549-558. <i>Date of Electronic Publication: </i>2018 Mar 20.
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