Anti-CTLA-4 therapy requires an Fc domain for efficacy. - Ingram JR; Blomberg OS; Rashidian M; Ali L; Garforth S; Fedorov E; Fedorov AA; Bonanno JB; Le Gall C; Crowley S; Espinosa C; Biary T; et al. (Proceedings of the National Academy of Sciences of the United States of America, 2018)