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Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model.

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Title: Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model.
Authors: Lu G; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Pine P; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Leeds JM; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., DeGuzman F; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Pratikhya P; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Lin J; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Malinowski J; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Hollenbach SJ; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Curnutte JT; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America., Conley PB; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.
Source: PloS one [PLoS One] 2018 Mar 28; Vol. 13 (3), pp. e0195122. Date of Electronic Publication: 2018 Mar 28 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model.
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  Data: <searchLink fieldCode="AU" term="%22Lu+G%22">Lu G</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Pine+P%22">Pine P</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Leeds+JM%22">Leeds JM</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22DeGuzman+F%22">DeGuzman F</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Pratikhya+P%22">Pratikhya P</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Malinowski+J%22">Malinowski J</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Hollenbach+SJ%22">Hollenbach SJ</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Curnutte+JT%22">Curnutte JT</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Conley+PB%22">Conley PB</searchLink>; Portola Pharmaceuticals Inc., South San Francisco, CA, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2018 Mar 28; Vol. 13 (3), pp. e0195122. <i>Date of Electronic Publication: </i>2018 Mar 28 (<i>Print Publication: </i>2018).
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        Value: 10.1371/journal.pone.0195122
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              Text: 2018 Mar 28
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