Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Saved in:
| Title: | Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. |
|---|---|
| Authors: | Zyryanova AF; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK. az310@cam.ac.uk ajw1000@cam.ac.uk dr360@medschl.cam.ac.uk., Weis F; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Faille A; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Alard AA; Division of Biomolecular Science and Medicinal Chemistry, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK., Crespillo-Casado A; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK., Sekine Y; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK., Harding HP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK., Allen F; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Parts L; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Fromont C; Division of Biomolecular Science and Medicinal Chemistry, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK., Fischer PM; Division of Biomolecular Science and Medicinal Chemistry, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK., Warren AJ; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK. az310@cam.ac.uk ajw1000@cam.ac.uk dr360@medschl.cam.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Ron D; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK. az310@cam.ac.uk ajw1000@cam.ac.uk dr360@medschl.cam.ac.uk. |
| Source: | Science (New York, N.Y.) [Science] 2018 Mar 30; Vol. 359 (6383), pp. 1533-1536. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1095-9203 |
|---|---|
| DOI: | 10.1126/science.aar5129 |
