Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors.
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| Title: | Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors. |
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| Authors: | Obach RS; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States., Walker GS; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States., Sharma R; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States., Jenkinson S; Pfizer Worldwide Research and Development , 10770 Science Center Drive , La Jolla , California 92121 , United States., Tran TP; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States., Stepan AF; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2018 Apr 26; Vol. 61 (8), pp. 3626-3640. Date of Electronic Publication: 2018 Apr 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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