Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
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| Title: | Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC). |
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| Authors: | Bergmeijer TO; St Antonius Center for Platelet Function Research, Department of Cardiology, St Antonius Hospital Nieuwegein, the Netherlands., Reny JL; Internal Medicine, Béziers Hospital, France, Geneva Platelet Group, University of Geneva School of Medicine, Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva, Switzerland., Pakyz RE; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Gong L; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Lewis JP; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Kim EY; Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, South Korea., Aradi D; Heart Center Balatonfüred and Heart and Vascular Center, Semmelweis University, Budapest, Hungary., Fernandez-Cadenas I; Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mútua Terrassa, Neurovascular Research Laboratory, Valle d'Hebron Hebron Institute of Research, Barcelona, Spain., Horenstein RB; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Lee MTM; Genomic Medicine Institute, Geisinger Health System, Danville, PA, USA., Whaley RM; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Montaner J; Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Barcelona, Spain., Gensini GF; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Cleator JH; Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA., Chang K; Cardiovascular Center and Cardiology Division, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Holmvang L; Department of Cardiology and Cardiac Catheterization Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Hochholzer W; University Heart Center Freiburg, Bad Krozingen, Department of Cardiology and Angiology II, Bad Krozingen, Germany., Roden DM; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA., Winter S; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany., Altman RB; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Departments of Bioengineering and Genetics, Stanford University, Stanford, CA, USA; Department of Medicine, Stanford University, Stanford, CA, USA., Alexopoulos D; Department of Cardiology, Patras University Hospital, Patras, Greece., Kim HS; Department of Pharmacology and Pharmacogenomics Research Center, College of Medicine, Inje University, Busan, South Korea., Déry JP; Quebec Heart and Lung Institute, Québec, Canada., Gawaz M; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany., Bliden K; Inova Center for Thrombosis Research and Drug Development. Inova Heart and Vascular Institute, Falls Church, VA, USA., Valgimigli M; Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, Bern, Switzerland., Marcucci R; Department of Experimental and Clinical Medicine, University of Florence, Atherothrombotic Diseases Center, Careggi Hospital, Florence, Italy., Campo G; Cardiology Unit, Azienda Ospedaliera Universitria di Ferrara, Cona (FE) and Maria Cecilia Hospital, GVM Care and Research, Cotignola, (RA), Italy., Schaeffeler E; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany., Dridi NP; Department of Cardiology and Cardiac Catheterization Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Wen MS; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou and School of Medicine, Chang Gung University, Taoyuan City, Taiwan., Shin JG; Department of Pharmacology and Pharmacogenomics Research Center, College of Medicine, Inje University, Busan, South Korea., Simon T; APHP, Saint Antoine Hospital, Paris, France., Fontana P; Geneva Platelet Group, University of Geneva School of Medicine, Division of Angiology and Haemostasis, University Hospitals of Geneva, Geneva, Switzerland., Giusti B; Department of Experimental and Clinical Medicine, University of Florence, Atherothrombotic Diseases Center, Careggi Hospital, Florence, Italy., Geisler T; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany., Kubo M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan., Trenk D; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany., Siller-Matula JM; Department of Cardiology, Medical University of Vienna, Vienna, Austria., Ten Berg JM; St Antonius Center for Platelet Function Research, Department of Cardiology, St Antonius Hospital Nieuwegein, the Netherlands., Gurbel PA; Inova Center for Thrombosis Research and Drug Development. Inova Heart and Vascular Institute, Falls Church, VA, USA., Hulot JS; Sorbonne Universités, UPMC Univ Paris 06, Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, F-75013 Paris, France., Mitchell BD; Department of Medicine, University of Maryland, Baltimore, MD, USA; Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Baltimore, MD., Schwab M; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany; Department of Clinical Pharmacology, University Hospital, Tübingen, Germany., Ritchie MD; Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, USA., Klein TE; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Department of Medicine, Stanford University, Stanford, CA, USA., Shuldiner AR; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: ashuldin@som.umaryland.edu. |
| Corporate Authors: | ICPC Investigators |
| Source: | American heart journal [Am Heart J] 2018 Apr; Vol. 198, pp. 152-159. Date of Electronic Publication: 2017 Dec 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29653637 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bergmeijer+TO%22">Bergmeijer TO</searchLink>; St Antonius Center for Platelet Function Research, Department of Cardiology, St Antonius Hospital Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Reny+JL%22">Reny JL</searchLink>; Internal Medicine, Béziers Hospital, France, Geneva Platelet Group, University of Geneva School of Medicine, Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pakyz+RE%22">Pakyz RE</searchLink>; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gong+L%22">Gong L</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+JP%22">Lewis JP</searchLink>; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kim+EY%22">Kim EY</searchLink>; Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, South Korea.<br /><searchLink fieldCode="AU" term="%22Aradi+D%22">Aradi D</searchLink>; Heart Center Balatonfüred and Heart and Vascular Center, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Fernandez-Cadenas+I%22">Fernandez-Cadenas I</searchLink>; Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mútua Terrassa, Neurovascular Research Laboratory, Valle d'Hebron Hebron Institute of Research, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Horenstein+RB%22">Horenstein RB</searchLink>; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lee+MTM%22">Lee MTM</searchLink>; Genomic Medicine Institute, Geisinger Health System, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Whaley+RM%22">Whaley RM</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Montaner+J%22">Montaner J</searchLink>; Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gensini+GF%22">Gensini GF</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Cleator+JH%22">Cleator JH</searchLink>; Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chang+K%22">Chang K</searchLink>; Cardiovascular Center and Cardiology Division, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Holmvang+L%22">Holmvang L</searchLink>; Department of Cardiology and Cardiac Catheterization Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hochholzer+W%22">Hochholzer W</searchLink>; University Heart Center Freiburg, Bad Krozingen, Department of Cardiology and Angiology II, Bad Krozingen, Germany.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Winter+S%22">Winter S</searchLink>; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Altman+RB%22">Altman RB</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Departments of Bioengineering and Genetics, Stanford University, Stanford, CA, USA; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alexopoulos+D%22">Alexopoulos D</searchLink>; Department of Cardiology, Patras University Hospital, Patras, Greece.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Pharmacology and Pharmacogenomics Research Center, College of Medicine, Inje University, Busan, South Korea.<br /><searchLink fieldCode="AU" term="%22Déry+JP%22">Déry JP</searchLink>; Quebec Heart and Lung Institute, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Gawaz+M%22">Gawaz M</searchLink>; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Bliden+K%22">Bliden K</searchLink>; Inova Center for Thrombosis Research and Drug Development. Inova Heart and Vascular Institute, Falls Church, VA, USA.<br /><searchLink fieldCode="AU" term="%22Valgimigli+M%22">Valgimigli M</searchLink>; Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marcucci+R%22">Marcucci R</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Atherothrombotic Diseases Center, Careggi Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Campo+G%22">Campo G</searchLink>; Cardiology Unit, Azienda Ospedaliera Universitria di Ferrara, Cona (FE) and Maria Cecilia Hospital, GVM Care and Research, Cotignola, (RA), Italy.<br /><searchLink fieldCode="AU" term="%22Schaeffeler+E%22">Schaeffeler E</searchLink>; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Dridi+NP%22">Dridi NP</searchLink>; Department of Cardiology and Cardiac Catheterization Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Wen+MS%22">Wen MS</searchLink>; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou and School of Medicine, Chang Gung University, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shin+JG%22">Shin JG</searchLink>; Department of Pharmacology and Pharmacogenomics Research Center, College of Medicine, Inje University, Busan, South Korea.<br /><searchLink fieldCode="AU" term="%22Simon+T%22">Simon T</searchLink>; APHP, Saint Antoine Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fontana+P%22">Fontana P</searchLink>; Geneva Platelet Group, University of Geneva School of Medicine, Division of Angiology and Haemostasis, University Hospitals of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Giusti+B%22">Giusti B</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Atherothrombotic Diseases Center, Careggi Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Geisler+T%22">Geisler T</searchLink>; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kubo+M%22">Kubo M</searchLink>; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Trenk+D%22">Trenk D</searchLink>; Department of Cardiology and Cardiovascular Medicine, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Siller-Matula+JM%22">Siller-Matula JM</searchLink>; Department of Cardiology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ten+Berg+JM%22">Ten Berg JM</searchLink>; St Antonius Center for Platelet Function Research, Department of Cardiology, St Antonius Hospital Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gurbel+PA%22">Gurbel PA</searchLink>; Inova Center for Thrombosis Research and Drug Development. Inova Heart and Vascular Institute, Falls Church, VA, USA.<br /><searchLink fieldCode="AU" term="%22Hulot+JS%22">Hulot JS</searchLink>; Sorbonne Universités, UPMC Univ Paris 06, Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, F-75013 Paris, France.<br /><searchLink fieldCode="AU" term="%22Mitchell+BD%22">Mitchell BD</searchLink>; Department of Medicine, University of Maryland, Baltimore, MD, USA; Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Schwab+M%22">Schwab M</searchLink>; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany; Department of Clinical Pharmacology, University Hospital, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ritchie+MD%22">Ritchie MD</searchLink>; Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Klein+TE%22">Klein TE</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shuldiner+AR%22">Shuldiner AR</searchLink>; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: ashuldin@som.umaryland.edu. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22ICPC+Investigators%22">ICPC Investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220370465%22">American heart journal</searchLink> [Am Heart J] 2018 Apr; Vol. 198, pp. 152-159. <i>Date of Electronic Publication: </i>2017 Dec 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370465 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200028703%22">00028703 </searchLink><i>NLM ISO Abbreviation: </i>Am Heart J <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ahj.2017.12.010 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 152 Titles: – TitleFull: Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bergmeijer TO – PersonEntity: Name: NameFull: Reny JL – PersonEntity: Name: NameFull: Pakyz RE – PersonEntity: Name: NameFull: Gong L – PersonEntity: Name: NameFull: Lewis JP – PersonEntity: Name: NameFull: Kim EY – PersonEntity: Name: NameFull: Aradi D – PersonEntity: Name: NameFull: Fernandez-Cadenas I – PersonEntity: Name: NameFull: Horenstein RB – PersonEntity: Name: NameFull: Lee MTM – PersonEntity: Name: NameFull: Whaley RM – PersonEntity: Name: NameFull: Montaner J – PersonEntity: Name: NameFull: Gensini GF – PersonEntity: Name: NameFull: Cleator JH – PersonEntity: Name: NameFull: Chang K – PersonEntity: Name: NameFull: Holmvang L – PersonEntity: Name: NameFull: Hochholzer W – PersonEntity: Name: NameFull: Roden DM – PersonEntity: Name: NameFull: Winter S – PersonEntity: Name: NameFull: Altman RB – PersonEntity: Name: NameFull: Alexopoulos D – PersonEntity: Name: NameFull: Kim HS – PersonEntity: Name: NameFull: Déry JP – PersonEntity: Name: NameFull: Gawaz M – PersonEntity: Name: NameFull: Bliden K – PersonEntity: Name: NameFull: Valgimigli M – PersonEntity: Name: NameFull: Marcucci R – PersonEntity: Name: NameFull: Campo G – PersonEntity: Name: NameFull: Schaeffeler E – PersonEntity: Name: NameFull: Dridi NP – PersonEntity: Name: NameFull: Wen MS – PersonEntity: Name: NameFull: Shin JG – PersonEntity: Name: NameFull: Simon T – PersonEntity: Name: NameFull: Fontana P – PersonEntity: Name: NameFull: Giusti B – PersonEntity: Name: NameFull: Geisler T – PersonEntity: Name: NameFull: Kubo M – PersonEntity: Name: NameFull: Trenk D – PersonEntity: Name: NameFull: Siller-Matula JM – PersonEntity: Name: NameFull: Ten Berg JM – PersonEntity: Name: NameFull: Gurbel PA – PersonEntity: Name: NameFull: Hulot JS – PersonEntity: Name: NameFull: Mitchell BD – PersonEntity: Name: NameFull: Schwab M – PersonEntity: Name: NameFull: Ritchie MD – PersonEntity: Name: NameFull: Klein TE – PersonEntity: Name: NameFull: Shuldiner AR IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2018 Apr Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 1097-6744 Numbering: – Type: volume Value: 198 Titles: – TitleFull: American heart journal Type: main |
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