Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT. - Parthasarathy S; Henry K; Pei H; Clayton J; Rempala M; Johns D; De Frutos O; Garcia P; Mateos C; Pleite S; Wang Y; Stout S; et al. (Bioorganic & medicinal chemistry letters, 2018)