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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.

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Title: A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.
Authors: Kovtun Y; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Jones GE; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Adams S; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Harvey L; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Audette CA; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Wilhelm A; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Bai C; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Rui L; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Laleau R; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Liu F; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Ab O; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Setiady Y; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Yoder NC; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Goldmacher VS; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Chari RVJ; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Pinkas J; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA., Chittenden T; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
Source: Blood advances [Blood Adv] 2018 Apr 24; Vol. 2 (8), pp. 848-858.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.
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