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A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors.

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Title: A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors.
Authors: Srivastava T; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Diba P; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Dean JM; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Banine F; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA., Shaver D; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Hagen M; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Gong X; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Su W; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA., Emery B; Department of Neurology, OHSU, Portland, Oregon, USA., Marks DL; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Harris EN; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA., Baggenstoss B; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Weigel PH; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Sherman LS; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.; Department of Cell, Developmental and Cancer Biology, OHSU, Portland, Oregon, USA., Back SA; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.; Department of Neurology, OHSU, Portland, Oregon, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2018 May 01; Vol. 128 (5), pp. 2025-2041. Date of Electronic Publication: 2018 Apr 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Srivastava+T%22">Srivastava T</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Diba+P%22">Diba P</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Dean+JM%22">Dean JM</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Banine+F%22">Banine F</searchLink>; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Shaver+D%22">Shaver D</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Hagen+M%22">Hagen M</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Gong+X%22">Gong X</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Su+W%22">Su W</searchLink>; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Emery+B%22">Emery B</searchLink>; Department of Neurology, OHSU, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Marks+DL%22">Marks DL</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Harris+EN%22">Harris EN</searchLink>; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Baggenstoss+B%22">Baggenstoss B</searchLink>; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Weigel+PH%22">Weigel PH</searchLink>; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Sherman+LS%22">Sherman LS</searchLink>; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.; Department of Cell, Developmental and Cancer Biology, OHSU, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Back+SA%22">Back SA</searchLink>; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.; Department of Neurology, OHSU, Portland, Oregon, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2018 May 01; Vol. 128 (5), pp. 2025-2041. <i>Date of Electronic Publication: </i>2018 Apr 16.
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