Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
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| Title: | Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. |
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| Authors: | Pardi N; Department of Medicine, University of Pennsylvania, Philadelphia, PA pnorbert@pennmedicine.upenn.edu., Hogan MJ; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Naradikian MS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Parkhouse K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Jones L; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Verkerke HP; Department of Medicinal Chemistry, University of Washington, Seattle, WA., Myles A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Willis E; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC., Lobby JL; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Liao HX; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Korber BT; Los Alamos National Laboratory, Los Alamos, NM., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Hraber PT; Los Alamos National Laboratory, Los Alamos, NM., Tombácz I; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Muramatsu H; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Ni H; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Balikov DA; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Li C; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Mui BL; Acuitas Therapeutics, Vancouver, BC, Canada., Tam YK; Acuitas Therapeutics, Vancouver, BC, Canada., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY., Karikó K; BioNTech RNA Pharmaceuticals, Mainz, Germany., Polacino P; Washington National Primate Research Center, University of Washington, Seattle, WA., Eisenlohr LC; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA., Madden TD; Acuitas Therapeutics, Vancouver, BC, Canada., Hope MJ; Acuitas Therapeutics, Vancouver, BC, Canada., Lewis MG; Bioqual Inc., Rockville, MD., Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA., Hu SL; Washington National Primate Research Center, University of Washington, Seattle, WA.; Department of Pharmaceutics, University of Washington, Seattle, WA., Hensley SE; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Cancro MP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, PA dreww@pennmedicine.upenn.edu. |
| Source: | The Journal of experimental medicine [J Exp Med] 2018 Jun 04; Vol. 215 (6), pp. 1571-1588. Date of Electronic Publication: 2018 May 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29739835 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pardi+N%22">Pardi N</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA pnorbert@pennmedicine.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Hogan+MJ%22">Hogan MJ</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Naradikian+MS%22">Naradikian MS</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Parkhouse+K%22">Parkhouse K</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Cain+DW%22">Cain DW</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Jones+L%22">Jones L</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Moody+MA%22">Moody MA</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Verkerke+HP%22">Verkerke HP</searchLink>; Department of Medicinal Chemistry, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Myles+A%22">Myles A</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Willis+E%22">Willis E</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22LaBranche+CC%22">LaBranche CC</searchLink>; Department of Surgery, Duke University Medical Center, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Department of Surgery, Duke University Medical Center, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Lobby+JL%22">Lobby JL</searchLink>; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Saunders+KO%22">Saunders KO</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Liao+HX%22">Liao HX</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Korber+BT%22">Korber BT</searchLink>; Los Alamos National Laboratory, Los Alamos, NM.<br /><searchLink fieldCode="AU" term="%22Sutherland+LL%22">Sutherland LL</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Scearce+RM%22">Scearce RM</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Hraber+PT%22">Hraber PT</searchLink>; Los Alamos National Laboratory, Los Alamos, NM.<br /><searchLink fieldCode="AU" term="%22Tombácz+I%22">Tombácz I</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Muramatsu+H%22">Muramatsu H</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Ni+H%22">Ni H</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Balikov+DA%22">Balikov DA</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Mui+BL%22">Mui BL</searchLink>; Acuitas Therapeutics, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Tam+YK%22">Tam YK</searchLink>; Acuitas Therapeutics, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Krammer+F%22">Krammer F</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Karikó+K%22">Karikó K</searchLink>; BioNTech RNA Pharmaceuticals, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Polacino+P%22">Polacino P</searchLink>; Washington National Primate Research Center, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Eisenlohr+LC%22">Eisenlohr LC</searchLink>; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Madden+TD%22">Madden TD</searchLink>; Acuitas Therapeutics, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Hope+MJ%22">Hope MJ</searchLink>; Acuitas Therapeutics, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lewis+MG%22">Lewis MG</searchLink>; Bioqual Inc., Rockville, MD.<br /><searchLink fieldCode="AU" term="%22Lee+KK%22">Lee KK</searchLink>; Department of Medicinal Chemistry, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Hu+SL%22">Hu SL</searchLink>; Washington National Primate Research Center, University of Washington, Seattle, WA.; Department of Pharmaceutics, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Hensley+SE%22">Hensley SE</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Cancro+MP%22">Cancro MP</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Haynes+BF%22">Haynes BF</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Weissman+D%22">Weissman D</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA dreww@pennmedicine.upenn.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2018 Jun 04; Vol. 215 (6), pp. 1571-1588. <i>Date of Electronic Publication: </i>2018 May 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Rockefeller+University+Press%22">Rockefeller University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985109R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1540-9538 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221007%22">00221007 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29739835 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1084/jem.20171450 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1571 Titles: – TitleFull: Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pardi N – PersonEntity: Name: NameFull: Hogan MJ – PersonEntity: Name: NameFull: Naradikian MS – PersonEntity: Name: NameFull: Parkhouse K – PersonEntity: Name: NameFull: Cain DW – PersonEntity: Name: NameFull: Jones L – PersonEntity: Name: NameFull: Moody MA – PersonEntity: Name: NameFull: Verkerke HP – PersonEntity: Name: NameFull: Myles A – PersonEntity: Name: NameFull: Willis E – PersonEntity: Name: NameFull: LaBranche CC – PersonEntity: Name: NameFull: Montefiori DC – PersonEntity: Name: NameFull: Lobby JL – PersonEntity: Name: NameFull: Saunders KO – PersonEntity: Name: NameFull: Liao HX – PersonEntity: Name: NameFull: Korber BT – PersonEntity: Name: NameFull: Sutherland LL – PersonEntity: Name: NameFull: Scearce RM – PersonEntity: Name: NameFull: Hraber PT – PersonEntity: Name: NameFull: Tombácz I – PersonEntity: Name: NameFull: Muramatsu H – PersonEntity: Name: NameFull: Ni H – PersonEntity: Name: NameFull: Balikov DA – PersonEntity: Name: NameFull: Li C – PersonEntity: Name: NameFull: Mui BL – PersonEntity: Name: NameFull: Tam YK – PersonEntity: Name: NameFull: Krammer F – PersonEntity: Name: NameFull: Karikó K – PersonEntity: Name: NameFull: Polacino P – PersonEntity: Name: NameFull: Eisenlohr LC – PersonEntity: Name: NameFull: Madden TD – PersonEntity: Name: NameFull: Hope MJ – PersonEntity: Name: NameFull: Lewis MG – PersonEntity: Name: NameFull: Lee KK – PersonEntity: Name: NameFull: Hu SL – PersonEntity: Name: NameFull: Hensley SE – PersonEntity: Name: NameFull: Cancro MP – PersonEntity: Name: NameFull: Haynes BF – PersonEntity: Name: NameFull: Weissman D IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 06 Text: 2018 Jun 04 Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 1540-9538 Numbering: – Type: volume Value: 215 – Type: issue Value: 6 Titles: – TitleFull: The Journal of experimental medicine Type: main |
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