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Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.

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Title: Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.
Authors: Marzi L; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Agama K; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Murai J; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Difilippantonio S; Laboratory of Animal Sciences Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland., James A; Laboratory of Animal Sciences Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland., Peer CJ; Clinical Pharmacology Program, Genitourinary Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Figg WD; Clinical Pharmacology Program, Genitourinary Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Beck D; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana., Elsayed MSA; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana., Cushman M; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana., Pommier Y; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. pommier@nih.gov.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2018 Aug; Vol. 17 (8), pp. 1694-1704. Date of Electronic Publication: 2018 May 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Marzi+L%22">Marzi L</searchLink>; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Agama+K%22">Agama K</searchLink>; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Murai+J%22">Murai J</searchLink>; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Difilippantonio+S%22">Difilippantonio S</searchLink>; Laboratory of Animal Sciences Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22James+A%22">James A</searchLink>; Laboratory of Animal Sciences Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Peer+CJ%22">Peer CJ</searchLink>; Clinical Pharmacology Program, Genitourinary Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Figg+WD%22">Figg WD</searchLink>; Clinical Pharmacology Program, Genitourinary Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Beck+D%22">Beck D</searchLink>; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana.<br /><searchLink fieldCode="AU" term="%22Elsayed+MSA%22">Elsayed MSA</searchLink>; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana.<br /><searchLink fieldCode="AU" term="%22Cushman+M%22">Cushman M</searchLink>; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, Lafayette, Indiana.<br /><searchLink fieldCode="AU" term="%22Pommier+Y%22">Pommier Y</searchLink>; Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. pommier@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101132535%22">Molecular cancer therapeutics</searchLink> [Mol Cancer Ther] 2018 Aug; Vol. 17 (8), pp. 1694-1704. <i>Date of Electronic Publication: </i>2018 May 10.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%2C+Inc%22">American Association for Cancer Research, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101132535 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-8514 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215357163%22">15357163 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer Ther <i>Subsets: </i>MEDLINE
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              Text: 2018 Aug
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