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Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.

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Title: Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.
Authors: Schott K; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Fuchs NV; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Derua R; Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, 3000, Leuven, Belgium.; Facility for Systems Biology based Mass Spectrometry (SYBIOMA), KU Leuven, 3000, Leuven, Belgium., Mahboubi B; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA., Schnellbächer E; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Seifried J; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Tondera C; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Schmitz H; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany., Shepard C; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA., Brandariz-Nuñez A; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Reuter A; Division of Allergology, Paul-Ehrlich-Institut, 63225, Langen, Germany., Kim B; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA.; Department of Pharmacy, Kyung-Hee University, 2447, Seoul, South Korea., Janssens V; Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, 3000, Leuven, Belgium., König R; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany. Renate.Koenig@pei.de.; Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA. Renate.Koenig@pei.de.; German Center for Infection Research (DZIF), 63225, Langen, Germany. Renate.Koenig@pei.de.
Source: Nature communications [Nat Commun] 2018 Jun 08; Vol. 9 (1), pp. 2227. Date of Electronic Publication: 2018 Jun 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.
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  Data: <searchLink fieldCode="AU" term="%22Schott+K%22">Schott K</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Fuchs+NV%22">Fuchs NV</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Derua+R%22">Derua R</searchLink>; Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, 3000, Leuven, Belgium.; Facility for Systems Biology based Mass Spectrometry (SYBIOMA), KU Leuven, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mahboubi+B%22">Mahboubi B</searchLink>; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Schnellbächer+E%22">Schnellbächer E</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Seifried+J%22">Seifried J</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Tondera+C%22">Tondera C</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitz+H%22">Schmitz H</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Shepard+C%22">Shepard C</searchLink>; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Brandariz-Nuñez+A%22">Brandariz-Nuñez A</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.<br /><searchLink fieldCode="AU" term="%22Diaz-Griffero+F%22">Diaz-Griffero F</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.<br /><searchLink fieldCode="AU" term="%22Reuter+A%22">Reuter A</searchLink>; Division of Allergology, Paul-Ehrlich-Institut, 63225, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; Center for Drug Discovery, Department of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA.; Department of Pharmacy, Kyung-Hee University, 2447, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Janssens+V%22">Janssens V</searchLink>; Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22König+R%22">König R</searchLink>; Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225, Langen, Germany. Renate.Koenig@pei.de.; Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA. Renate.Koenig@pei.de.; German Center for Infection Research (DZIF), 63225, Langen, Germany. Renate.Koenig@pei.de.
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