Induction and transcriptional regulation of the co-inhibitory gene module in T cells.

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Title: Induction and transcriptional regulation of the co-inhibitory gene module in T cells.
Authors: Chihara N; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Madi A; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kondo T; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Zhang H; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Acharya N; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Singer M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nyman J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Marjanovic ND; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kowalczyk MS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Celsius Therapeutics, Cambridge, MA, USA., Wang C; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Kurtulus S; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Law T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Etminan Y; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Nevin J; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Buckley CD; Rheumatology Research Group, Center for Translational Inflammation Research, Queen Elizabeth Hospital, Birmingham, UK., Burkett PR; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Pulmonary and Critical Care Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Buenrostro JD; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rozenblatt-Rosen O; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Anderson AC; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA. acanderson@partners.org.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. acanderson@partners.org., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA. aregev@broadinstitute.org.; Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. aregev@broadinstitute.org.; Department of Biology, Koch Institute and Ludwig Center, Massachusetts Institute of Technology, Cambridge, MA, USA. aregev@broadinstitute.org., Kuchroo VK; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA. vkuchroo@evergrande.hms.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. vkuchroo@evergrande.hms.harvard.edu.
Source: Nature [Nature] 2018 Jun; Vol. 558 (7710), pp. 454-459. Date of Electronic Publication: 2018 Jun 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Singer+M%22">Singer M</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nyman+J%22">Nyman J</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Marjanovic+ND%22">Marjanovic ND</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kowalczyk+MS%22">Kowalczyk MS</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Celsius Therapeutics, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kurtulus+S%22">Kurtulus S</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Law+T%22">Law T</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Etminan+Y%22">Etminan Y</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nevin+J%22">Nevin J</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buckley+CD%22">Buckley CD</searchLink>; Rheumatology Research Group, Center for Translational Inflammation Research, Queen Elizabeth Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Burkett+PR%22">Burkett PR</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Pulmonary and Critical Care Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buenrostro+JD%22">Buenrostro JD</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rozenblatt-Rosen+O%22">Rozenblatt-Rosen O</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+AC%22">Anderson AC</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA. acanderson@partners.org.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. acanderson@partners.org.<br /><searchLink fieldCode="AU" term="%22Regev+A%22">Regev A</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA. aregev@broadinstitute.org.; Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. aregev@broadinstitute.org.; Department of Biology, Koch Institute and Ludwig Center, Massachusetts Institute of Technology, Cambridge, MA, USA. aregev@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Kuchroo+VK%22">Kuchroo VK</searchLink>; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA. vkuchroo@evergrande.hms.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. vkuchroo@evergrande.hms.harvard.edu.
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