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Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.

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Title: Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.
Authors: Aguirre AJ; Dana-Farber Cancer Institute, Boston, Massachusetts. andrew_aguirre@dfci.harvard.edu carter.scott@jimmy.harvard.edu brian_wolpin@dfci.harvard.edu.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Nowak JA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Camarda ND; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Moffitt RA; Department of Biomedical Informatics, Department of Pathology, Stony Brook University, Stony Brook, New York., Ghazani AA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Hazar-Rethinam M; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Raghavan S; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Kim J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Brais LK; Dana-Farber Cancer Institute, Boston, Massachusetts., Ragon D; Dana-Farber Cancer Institute, Boston, Massachusetts., Welch MW; Dana-Farber Cancer Institute, Boston, Massachusetts., Reilly E; Dana-Farber Cancer Institute, Boston, Massachusetts., McCabe D; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Marini L; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Anderka K; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Helvie K; Dana-Farber Cancer Institute, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Oliver N; Dana-Farber Cancer Institute, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Babic A; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Da Silva A; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Nadres B; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Van Seventer EE; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Shahzade HA; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., St Pierre JP; Dana-Farber Cancer Institute, Boston, Massachusetts., Burke KP; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Clancy T; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Cleary JM; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Doyle LA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Jajoo K; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts., McCleary NJ; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Meyerhardt JA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Murphy JE; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Ng K; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Patel AK; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Perez K; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Rosenthal MH; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts., Rubinson DA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Ryou M; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts., Shapiro GI; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Sicinska E; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Silverman SG; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts., Nagy RJ; Department of Medical Affairs, Guardant Health, Inc., Redwood City, California., Lanman RB; Department of Medical Affairs, Guardant Health, Inc., Redwood City, California., Knoerzer D; BioMed Valley Discoveries, Kansas City, Missouri., Welsch DJ; BioMed Valley Discoveries, Kansas City, Missouri., Yurgelun MB; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Fuchs CS; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Garraway LA; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Getz G; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Hornick JL; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Johnson BE; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Kulke MH; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Mayer RJ; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Miller JW; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Shyn PB; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts., Tuveson DA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Wagle N; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts., Yeh JJ; Departments of Surgery and Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina., Hahn WC; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Corcoran RB; Harvard Medical School, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Carter SL; Dana-Farber Cancer Institute, Boston, Massachusetts. andrew_aguirre@dfci.harvard.edu carter.scott@jimmy.harvard.edu brian_wolpin@dfci.harvard.edu.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Wolpin BM; Dana-Farber Cancer Institute, Boston, Massachusetts. andrew_aguirre@dfci.harvard.edu carter.scott@jimmy.harvard.edu brian_wolpin@dfci.harvard.edu.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.
Source: Cancer discovery [Cancer Discov] 2018 Sep; Vol. 8 (9), pp. 1096-1111. Date of Electronic Publication: 2018 Jun 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
An: 29903880
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.
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Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Moffitt+RA%22">Moffitt RA</searchLink>; Department of Biomedical Informatics, Department of Pathology, Stony Brook University, Stony Brook, New York.<br /><searchLink fieldCode="AU" term="%22Ghazani+AA%22">Ghazani AA</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hazar-Rethinam+M%22">Hazar-Rethinam M</searchLink>; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Raghavan+S%22">Raghavan S</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Brais+LK%22">Brais LK</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ragon+D%22">Ragon D</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Welch+MW%22">Welch MW</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Reilly+E%22">Reilly E</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22McCabe+D%22">McCabe D</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. 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Harvard T.H. Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Garraway+LA%22">Garraway LA</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Getz+G%22">Getz G</searchLink>; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hornick+JL%22">Hornick JL</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Johnson+BE%22">Johnson BE</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kulke+MH%22">Kulke MH</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Mayer+RJ%22">Mayer RJ</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Miller+JW%22">Miller JW</searchLink>; Harvard T.H. Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Shyn+PB%22">Shyn PB</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Tuveson+DA%22">Tuveson DA</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.<br /><searchLink fieldCode="AU" term="%22Wagle+N%22">Wagle N</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Yeh+JJ%22">Yeh JJ</searchLink>; Departments of Surgery and Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.<br /><searchLink fieldCode="AU" term="%22Hahn+WC%22">Hahn WC</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Corcoran+RB%22">Corcoran RB</searchLink>; Harvard Medical School, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Carter+SL%22">Carter SL</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts. andrew_aguirre@dfci.harvard.edu carter.scott@jimmy.harvard.edu brian_wolpin@dfci.harvard.edu.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Wolpin+BM%22">Wolpin BM</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts. andrew_aguirre@dfci.harvard.edu carter.scott@jimmy.harvard.edu brian_wolpin@dfci.harvard.edu.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2018 Sep; Vol. 8 (9), pp. 1096-1111. <i>Date of Electronic Publication: </i>2018 Jun 14.
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            NameFull: Van Seventer EE
      – PersonEntity:
          Name:
            NameFull: Shahzade HA
      – PersonEntity:
          Name:
            NameFull: St Pierre JP
      – PersonEntity:
          Name:
            NameFull: Burke KP
      – PersonEntity:
          Name:
            NameFull: Clancy T
      – PersonEntity:
          Name:
            NameFull: Cleary JM
      – PersonEntity:
          Name:
            NameFull: Doyle LA
      – PersonEntity:
          Name:
            NameFull: Jajoo K
      – PersonEntity:
          Name:
            NameFull: McCleary NJ
      – PersonEntity:
          Name:
            NameFull: Meyerhardt JA
      – PersonEntity:
          Name:
            NameFull: Murphy JE
      – PersonEntity:
          Name:
            NameFull: Ng K
      – PersonEntity:
          Name:
            NameFull: Patel AK
      – PersonEntity:
          Name:
            NameFull: Perez K
      – PersonEntity:
          Name:
            NameFull: Rosenthal MH
      – PersonEntity:
          Name:
            NameFull: Rubinson DA
      – PersonEntity:
          Name:
            NameFull: Ryou M
      – PersonEntity:
          Name:
            NameFull: Shapiro GI
      – PersonEntity:
          Name:
            NameFull: Sicinska E
      – PersonEntity:
          Name:
            NameFull: Silverman SG
      – PersonEntity:
          Name:
            NameFull: Nagy RJ
      – PersonEntity:
          Name:
            NameFull: Lanman RB
      – PersonEntity:
          Name:
            NameFull: Knoerzer D
      – PersonEntity:
          Name:
            NameFull: Welsch DJ
      – PersonEntity:
          Name:
            NameFull: Yurgelun MB
      – PersonEntity:
          Name:
            NameFull: Fuchs CS
      – PersonEntity:
          Name:
            NameFull: Garraway LA
      – PersonEntity:
          Name:
            NameFull: Getz G
      – PersonEntity:
          Name:
            NameFull: Hornick JL
      – PersonEntity:
          Name:
            NameFull: Johnson BE
      – PersonEntity:
          Name:
            NameFull: Kulke MH
      – PersonEntity:
          Name:
            NameFull: Mayer RJ
      – PersonEntity:
          Name:
            NameFull: Miller JW
      – PersonEntity:
          Name:
            NameFull: Shyn PB
      – PersonEntity:
          Name:
            NameFull: Tuveson DA
      – PersonEntity:
          Name:
            NameFull: Wagle N
      – PersonEntity:
          Name:
            NameFull: Yeh JJ
      – PersonEntity:
          Name:
            NameFull: Hahn WC
      – PersonEntity:
          Name:
            NameFull: Corcoran RB
      – PersonEntity:
          Name:
            NameFull: Carter SL
      – PersonEntity:
          Name:
            NameFull: Wolpin BM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2018 Sep
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 2159-8290
          Numbering:
            – Type: volume
              Value: 8
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Cancer discovery
              Type: main
ResultId 1