Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Saved in:
| Title: | Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. |
|---|---|
| Authors: | Viswanathan SR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Nogueira MF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Buss CG; Harvard-MIT Department of Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Boston, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Krill-Burger JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wawer MJ; Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Malolepsza E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Berger AC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Choi PS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Shih J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Taylor AM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Tanenbaum B; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pedamallu CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Cherniack AD; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tamayo P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; UCSD Moores Cancer Center and Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Strathdee CA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lage K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schenone M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bhatia SN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Harvard-MIT Department of Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Boston, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Vazquez F; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tsherniak A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Meyerson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. matthew_meyerson@dfci.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. matthew_meyerson@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. matthew_meyerson@dfci.harvard.edu. |
| Source: | Nature genetics [Nat Genet] 2018 Jul; Vol. 50 (7), pp. 937-943. Date of Electronic Publication: 2018 Jun 28. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
