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The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort.

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Title: The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort.
Authors: Tariot PN; Banner Alzheimer's Institute, Phoenix, AZ, USA., Lopera F; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Langbaum JB; Banner Alzheimer's Institute, Phoenix, AZ, USA., Thomas RG; Department of Neurosciences, University of California San Diego School of Medicine, La Jolla, CA, USA., Hendrix S; Pentara Corporation, Salt Lake City, UT, USA., Schneider LS; USC State of California Alzheimer's Disease Research and Clinical Center, Keck Medicine of USC, Los Angeles, CA, USA., Rios-Romenets S; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Giraldo M; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Acosta N; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Tobon C; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Ramos C; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Espinosa A; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Cho W; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Ward M; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Clayton D; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Friesenhahn M; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Mackey H; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Honigberg L; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Sanabria Bohorquez S; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Chen K; Banner Alzheimer's Institute, Phoenix, AZ, USA., Walsh T; Banner Alzheimer's Institute, Phoenix, AZ, USA., Langlois C; Banner Alzheimer's Institute, Phoenix, AZ, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
Corporate Authors: Alzheimer's Prevention Initiative
Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2018 Mar 08; Vol. 4, pp. 150-160. Date of Electronic Publication: 2018 Mar 08 (Print Publication: 2018).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort.
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  Data: <searchLink fieldCode="AU" term="%22Tariot+PN%22">Tariot PN</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Lopera+F%22">Lopera F</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Langbaum+JB%22">Langbaum JB</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+RG%22">Thomas RG</searchLink>; Department of Neurosciences, University of California San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hendrix+S%22">Hendrix S</searchLink>; Pentara Corporation, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+LS%22">Schneider LS</searchLink>; USC State of California Alzheimer's Disease Research and Clinical Center, Keck Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rios-Romenets+S%22">Rios-Romenets S</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Giraldo+M%22">Giraldo M</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Acosta+N%22">Acosta N</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Tobon+C%22">Tobon C</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Ramos+C%22">Ramos C</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Espinosa+A%22">Espinosa A</searchLink>; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Cho+W%22">Cho W</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ward+M%22">Ward M</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Clayton+D%22">Clayton D</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Friesenhahn+M%22">Friesenhahn M</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mackey+H%22">Mackey H</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Honigberg+L%22">Honigberg L</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sanabria+Bohorquez+S%22">Sanabria Bohorquez S</searchLink>; Genentech, a Member of the Roche Group, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Walsh+T%22">Walsh T</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Langlois+C%22">Langlois C</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Reiman+EM%22">Reiman EM</searchLink>; Banner Alzheimer's Institute, Phoenix, AZ, USA.
– Name: AuthorCorporate
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  Data: <searchLink fieldCode="CA" term="%22Alzheimer's+Prevention+Initiative%22">Alzheimer's Prevention Initiative</searchLink>
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101650118 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-8737 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528737%22">23528737 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (N Y) <i>Subsets: </i>PubMed not MEDLINE
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