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Psychopharmacological effects and safety of styryl-2-pyrones and dihydrostyryl-2-pyrones-rich fraction from Polygala sabulosa: absence of withdrawal syndrome and tolerance to anxiolytic-like and anticonvulsant effects.

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Title: Psychopharmacological effects and safety of styryl-2-pyrones and dihydrostyryl-2-pyrones-rich fraction from Polygala sabulosa: absence of withdrawal syndrome and tolerance to anxiolytic-like and anticonvulsant effects.
Authors: Duarte FS; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Pernambuco, Brazil., Duzzioni M; Institute of Biological Sciences and Health, Federal University of Alagoas, Maceió, Alagoas, Brazil., Prim RL; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Cardozo AM; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Dos Santos CR; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., da Silva MG; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Shiozawa MBC; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Mendes BG; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Tizziani T; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Brighente IMC; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Pizzolatti MG; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., de Lima TCM; Department of Pharmacology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Source: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2018 Sep; Vol. 70 (9), pp. 1272-1286. Date of Electronic Publication: 2018 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Psychopharmacological effects and safety of styryl-2-pyrones and dihydrostyryl-2-pyrones-rich fraction from Polygala sabulosa: absence of withdrawal syndrome and tolerance to anxiolytic-like and anticonvulsant effects.
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  Data: <searchLink fieldCode="AU" term="%22Duarte+FS%22">Duarte FS</searchLink>; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Pernambuco, Brazil.<br /><searchLink fieldCode="AU" term="%22Duzzioni+M%22">Duzzioni M</searchLink>; Institute of Biological Sciences and Health, Federal University of Alagoas, Maceió, Alagoas, Brazil.<br /><searchLink fieldCode="AU" term="%22Prim+RL%22">Prim RL</searchLink>; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Cardozo+AM%22">Cardozo AM</searchLink>; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+CR%22">Dos Santos CR</searchLink>; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+MG%22">da Silva MG</searchLink>; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Shiozawa+MBC%22">Shiozawa MBC</searchLink>; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Mendes+BG%22">Mendes BG</searchLink>; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Tizziani+T%22">Tizziani T</searchLink>; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Brighente+IMC%22">Brighente IMC</searchLink>; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22Pizzolatti+MG%22">Pizzolatti MG</searchLink>; Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Lima+TCM%22">de Lima TCM</searchLink>; Department of Pharmacology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
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  Data: <searchLink fieldCode="JN" term="%220376363%22">The Journal of pharmacy and pharmacology</searchLink> [J Pharm Pharmacol] 2018 Sep; Vol. 70 (9), pp. 1272-1286. <i>Date of Electronic Publication: </i>2018 Jun 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0376363 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2042-7158 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223573%22">00223573 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Pharmacol <i>Subsets: </i>MEDLINE
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