Simvastatin Treatment Protects Myocardium in Noncoronary Artery Cardiac Surgery by Inhibiting Apoptosis Through miR-15a-5p Targeting.
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| Title: | Simvastatin Treatment Protects Myocardium in Noncoronary Artery Cardiac Surgery by Inhibiting Apoptosis Through miR-15a-5p Targeting. |
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| Authors: | Zhou L; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Liu X; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Wang ZQ; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Li Y; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Shi MM; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Xu Z; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Ou ZJ; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China.; Division of Hypertension and Vascular Diseases, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China., Li HM; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Cheng TP; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Jian YP; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China., Zhang W; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Liu C; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China.; Department of Cardiology, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China., Zhang X; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Quon MJ; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD., Zhang CX; Department of Biomedical Engineering, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL., Xu YQ; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Wang ZP; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China., Ou JS; Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.; The Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, P.R. China.; National and Guangdong Province Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, P.R. China.; Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangzhou, P.R. China. |
| Source: | Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2018 Oct; Vol. 72 (4), pp. 176-185. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Print Cited Medium: Internet ISSN: 1533-4023 (Electronic) Linking ISSN: 01602446 NLM ISO Abbreviation: J Cardiovasc Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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