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IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

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Title: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Authors: Urra H; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Henriquez DR; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile., Cánovas J; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile., Villarroel-Campos D; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile., Carreras-Sureda A; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Pulgar E; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Anatomy and Developmental Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Molina E; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Center for Genome Regulation, Faculty of Sciences, University of Chile, Santiago, Chile., Hazari YM; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Limia CM; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Alvarez-Rojas S; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile., Figueroa R; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Vidal RL; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile., Rodriguez DA; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Rivera CA; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile., Court FA; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile., Couve A; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Department of Neuroscience, Faculty of Medicine, University of Chile, Santiago, Chile., Qi L; Department of Molecular and Integrative Physiology, Division of Metabolism, Endocrinology and Diabetes, The University of Michigan Medical School, Ann Arbor, MI, USA., Chevet E; INSERM U1242 Chemistry, Oncogenesis, Stress and Signaling, University of Rennes 1, Rennes, France.; Centre de Lutte contre le Cancer Eugène Marquis, Rennes, France., Akai R; Division of Cell Medicine, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Japan., Iwawaki T; Division of Cell Medicine, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Japan., Concha ML; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Anatomy and Developmental Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile., Glavic Á; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Center for Genome Regulation, Faculty of Sciences, University of Chile, Santiago, Chile., Gonzalez-Billault C; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile., Hetz C; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile. chetz@med.uchile.cl.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile. chetz@med.uchile.cl.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile. chetz@med.uchile.cl.; The Buck Institute for Research in Aging, Novato, CA, USA. chetz@med.uchile.cl.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA. chetz@med.uchile.cl.
Source: Nature cell biology [Nat Cell Biol] 2018 Aug; Vol. 20 (8), pp. 942-953. Date of Electronic Publication: 2018 Jul 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
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  Data: <searchLink fieldCode="AU" term="%22Urra+H%22">Urra H</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Henriquez+DR%22">Henriquez DR</searchLink>; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Cánovas+J%22">Cánovas J</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Villarroel-Campos+D%22">Villarroel-Campos D</searchLink>; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Carreras-Sureda+A%22">Carreras-Sureda A</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Pulgar+E%22">Pulgar E</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Anatomy and Developmental Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Molina+E%22">Molina E</searchLink>; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Center for Genome Regulation, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Hazari+YM%22">Hazari YM</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Limia+CM%22">Limia CM</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Alvarez-Rojas+S%22">Alvarez-Rojas S</searchLink>; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Figueroa+R%22">Figueroa R</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Vidal+RL%22">Vidal RL</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Rodriguez+DA%22">Rodriguez DA</searchLink>; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Rivera+CA%22">Rivera CA</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Court+FA%22">Court FA</searchLink>; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Couve+A%22">Couve A</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Department of Neuroscience, Faculty of Medicine, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Qi+L%22">Qi L</searchLink>; Department of Molecular and Integrative Physiology, Division of Metabolism, Endocrinology and Diabetes, The University of Michigan Medical School, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Chevet+E%22">Chevet E</searchLink>; INSERM U1242 Chemistry, Oncogenesis, Stress and Signaling, University of Rennes 1, Rennes, France.; Centre de Lutte contre le Cancer Eugène Marquis, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Akai+R%22">Akai R</searchLink>; Division of Cell Medicine, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Japan.<br /><searchLink fieldCode="AU" term="%22Iwawaki+T%22">Iwawaki T</searchLink>; Division of Cell Medicine, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Japan.<br /><searchLink fieldCode="AU" term="%22Concha+ML%22">Concha ML</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Program of Anatomy and Developmental Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Glavic+Á%22">Glavic Á</searchLink>; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Center for Genome Regulation, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Billault+C%22">Gonzalez-Billault C</searchLink>; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile.; Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Hetz+C%22">Hetz C</searchLink>; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile. chetz@med.uchile.cl.; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile. chetz@med.uchile.cl.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile. chetz@med.uchile.cl.; The Buck Institute for Research in Aging, Novato, CA, USA. chetz@med.uchile.cl.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA. chetz@med.uchile.cl.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2018 Aug; Vol. 20 (8), pp. 942-953. <i>Date of Electronic Publication: </i>2018 Jul 16.
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